NCT07268404 · Daily Nouri
Women's Hormonal and Metabolic Wellbeing Study
What this study is about
The goal of this clinical trial is to learn if Daily Nouri Hormone Balance Probiotic blend can improve metabolic, inflammatory, and symptom outcomes in women.
View original scientific description
The goal of this clinical trial is to learn if Daily Nouri Hormone Balance Probiotic blend can improve metabolic, inflammatory, and symptom outcomes in women.
Interventions
DIETARY_SUPPLEMENT
Probiotic Blend Capsule
Hormone Balance Probiotic Blend
DIETARY_SUPPLEMENT
Placebo
Placebo
Primary outcome measures
Women's Health Quality of Life Scores
Time frame: From baseline to week 12
Women's Health Quality of Life as measured by changes in total and domains scores on the Health-Related Quality of Life Questionnaire for Polycystic Ovary Syndrome-26 (PCOSQ-26). Response Scale: 7-Point Likert Scale Per-Item Range: minimum: 1, maximum: 7, where higher scores indicate better outcomes.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Self-reported irregular menstrual cycles, defined as one or more of the following:
- Cycle length typically \>35 days OR \<21 days
- Fewer than 9 menstrual periods in the past year
- Unpredictable cycle timing (varies by \>7 days month-to-month)
- Irregular cycles present for ≥6 months
- One or more of the following hormonal balance concerns: skin, unwanted hair growth, hair thinning, weight concerns)
- Self-reported emotional symptoms that fluctuate with menstrual cycle, including:
- Mood swings or irritability
- Feelings of stress or tension
- Low mood or feeling down
- Difficulty with emotional regulation
- Not currently using hormonal therapies, metformin, GLP-1 receptor agonists, or anti-androgens.
- If taking supplements for menstrual/hormonal support: willing to discontinue for 2-week washout before baseline
- Weight stable (+ 5 pounds) for the past 2 months, not planning to start a new diet, exercise program, or medications during study
- Able to provide electronic informed consent.
- Willing to complete online surveys and at-home DBS sample collection.
- Negative home pregnancy test at baseline.
- Access to a computer or smartphone and reliable internet connection.
Where
- San Francisco, California
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Dec 19, 2025 · Source of record for eligibility and locations