Baltimore, MDNCT07247058Now EnrollingIRB Ready

Mild Autonomous Cortisol Secretion (MACS) Clinical Trial in Baltimore, MD

Access cutting-edge mild autonomous cortisol secretion (macs) treatment through this clinical trial at a research site in Baltimore. Study-provided care at no cost to qualified participants.

Sponsored by Johns Hopkins University

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Expert Care in Baltimore

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related mild autonomous cortisol secretion (macs) treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Baltimore

    Convenient for MD residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Baltimore site if eligible
  4. 4Begin participation

About This Mild Autonomous Cortisol Secretion (MACS) Study in Baltimore

To characterize the impact of Isturisa on clinical features and comorbidities associated with MACS. The investigators hypothesize that patients treated with Isturisa will exhibit significantly better metabolic indicators (such as fasting glucose, HbA1c, and lipid profile), blood pressure, weight, body composition and bone mineral density than at Baseline. The investigators also assess the effect of Isturisa on quality of life and psychological symptoms in patients with MACS. The investigators hypothesize that treatment with Isturisa will lead to significant improvements in quality-of-life scores and reductions in depression scores compared to Baseline.

Sponsor: Johns Hopkins University

Who Can Participate

Inclusion Criteria

Adults aged ≥18 years.
Diagnosis of mild autonomous cortisol secretion (MACS) defined by:
Serum cortisol \>1.8 µg/dL after 1 mg overnight dexamethasone suppression test (DST).
Presence of adrenal adenoma confirmed by imaging (CT or MRI).
Ability to provide informed consent.
Willingness to undergo study procedures including DEXA scan and laboratory assessments.

Exclusion Criteria

Known diagnosis of Cushing's syndrome or overt hypercortisolism.
Current or recent (within 3 months) treatment with glucocorticoids or medications affecting cortisol production (e.g., ketoconazole, metyrapone).
Severe hepatic impairment or renal failure.
Pregnancy or breastfeeding.
Known allergy or contraindication to osilodrostat (Isturisa).
Participation in another interventional clinical trial within the last 30 days.
Any medical or psychiatric condition that, in the investigator's judgment, may interfere with study participation or safety.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Baltimore?

Yes, this clinical trial (NCT07247058) has an active research site in Baltimore, MD that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Mild Autonomous Cortisol Secretion (MACS) Treatment Options in Baltimore, MD

If you're searching for mild autonomous cortisol secretion (macs) treatment options in Baltimore, MD, this clinical trial (NCT07247058) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Baltimore research site is actively enrolling participants for this clinical trial. You'll receive care from experienced mild autonomous cortisol secretion (macs) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all mild autonomous cortisol secretion (macs) clinical trials near you to find additional studies recruiting in your area.

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