High Point, NCNCT07097051Now EnrollingIRB Ready

Mild Cognitive Impairment (MCI) Clinical Trial in High Point, NC

Access cutting-edge mild cognitive impairment (mci) treatment through this clinical trial at a research site in High Point. Study-provided care at no cost to qualified participants.

Sponsored by High Point University

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Expert Care in High Point

Access mild cognitive impairment (mci) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related mild cognitive impairment (mci) treatment provided free

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Check if you qualify for this mild cognitive impairment (mci) clinical trial in High Point, NC

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Why Participate?

  • No-Cost Study Care

  • Local to High Point

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit High Point site if eligible
  4. 4Begin participation

About This Mild Cognitive Impairment (MCI) Study in High Point

Older adults with Mild Cognitive Impairment (MCI) often show less brain activity in a specific range (8-13 Hz, known as alpha power) compared to healthy older adults. Those with lower alpha activity, especially in the front part of the brain, usually have problems with executive functions like planning and multitasking. Our research has shown that older adults with lower alpha power in these areas also struggle more with balance when they have to do two things at once (like standing and performing a cognitive task simultaneously). The investigators believe that increasing alpha power in older adults with MCI could improve their balance and executive function, helping them stay independent longer. In early studies, the investigators found that using transcranial alternating current stimulation (tACS) at 10 Hz on the front part of the brain can boost alpha power and balance immediately after a single session in older adults with MCI. The effect was stronger in those whose natural brain activity was close to the 10 Hz stimulation. Based on these findings, the investigators plan to conduct a pilot study with older adults aged 65-85 years with MCI. Participants will be randomly assigned to receive either real tACS or a sham (placebo) treatment. Our main hypothesis is that real tACS will improve balance when multitasking, and these improvements will last for 1 to 3 months after the treatment. The investigators also believe that tACS will enhance other aspects of executive function and mobility and that these improvements will be linked to increased alpha activity in the brain. Through this study, we aim to gather strong evidence that tailored tACS is a promising treatment to improve cognitive and motor functions and overall brain activity in older adults with MCI.

Sponsor: High Point University

Who Can Participate

Inclusion Criteria

Who have been diagnosed with cognitive impairment (based in MoCA or TICS and Clinical Dementia Rating: CDR 0.5)
Ability to stand and walk independently
Willing and capable to give informed consent for the participation in the study after it has been thoroughly explained
Cut off of MOCA score \>18 will be applied
Able and willing to comply with all study requirements informed consent form was signed
Understanding of the ICF will be assessed by asking the participant to answer the following three questions: 1) What is the purpose of this study? 2) What are the risks of study involvement? 3) If you decide to participate, are you allowed to withdraw from the study at any time? Answers will be recorded by study personnel on the "Assessment of Protocol Understanding" form (see attached). Insufficient understanding will be defined by one or more incorrect answers, as determined at the discretion of the investigator.

Exclusion Criteria

Cut off of MOCA score \<18 will be applied
Major psychiatric co-morbidity including major depressive disorder, schizophrenia or psychosis
Blindness or other disabilities that prevent task performance
Self-reported history of stroke or neurodegenerative disorders other than MCI.
Self-reported active cancer for which chemo-/radiation therapy is being received.
Contraindications to tACS, as recorded on a standardized screening questionnaire, which include a reported seizure within the past two years, use of neuro-active drugs, self-reported presence of specific implanted medical devices (e.g., deep brain stimulator, medication infusion pump, cochlear implant, pacemaker, etc.), or the presence of any active dermatological condition, such as eczema, on the scalp.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in High Point?

Yes, this clinical trial (NCT07097051) has an active research site in High Point, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Mild Cognitive Impairment (MCI) Treatment Options in High Point, NC

If you're searching for mild cognitive impairment (mci) treatment options in High Point, NC, this clinical trial (NCT07097051) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our High Point research site is actively enrolling participants for this clinical trial. You'll receive care from experienced mild cognitive impairment (mci) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all mild cognitive impairment (mci) clinical trials near you to find additional studies recruiting in your area.

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