Aurora, CONCT05822362Now EnrollingIRB Ready

Mild Cognitive Impairment Clinical Trial in Aurora, CO

Access cutting-edge mild cognitive impairment treatment through this clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by University of Colorado, Denver

Quick Self-Assessment

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Expert Care in Aurora

Access mild cognitive impairment specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related mild cognitive impairment treatment provided free

Apply for This Aurora Location

Check if you qualify for this mild cognitive impairment clinical trial in Aurora, CO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This Mild Cognitive Impairment Study in Aurora

This is a double-blind, randomized controlled trial designed to test the effects of cannabidiol (CBD) on validated biomarkers of Alzheimer's disease (AD) progression, and behavioral, neurocognitive, and clinical measures, with putative mechanisms of action.

Sponsor: University of Colorado, Denver

Who Can Participate

Inclusion Criteria

Must be between the ages of 55 - 85 and provide valid informed consent.
Participant must receive a diagnosis of Mild Cognitive Impairment after a careful cognitive and functional evaluation by a clinician, or have symptoms of Mild Cognitive Impairment as determined by the study physician.
Functional Activities Questionnaire (FAQ) score of 8 or less and self-reported ability to function independently.
Montreal Cognitive Assessment (MoCa) score is ≤ 25
Participant must have a CDR score of .5 or 1 on the Clinical Dementia Rating scale (CDR), which includes an assessment of function and is often used to distinguish MCI from dementia. A score of 0.5 indicates mild cognitive impairment but not dementia and a score of 1 indicates mild-to-moderate cognitive impairment.
Must have an informant that will be utilized over the course of the 24 week study (must be the same person for all CDR assessments completed via phone).
Participant must pass a test of consent comprehension
Must be interested in using CBD to help with cognitive function
Must plan on living in the Denver metro area over the next 6 months
Able to attend in-person visits at the study site

Exclusion Criteria

Any other central nervous system (CNS) disease that would be expected to affect cognition, Parkinson's disease, multiple sclerosis.
History of brain injury resulting in current memory loss symptoms (e.g., concussion with significant loss of consciousness)
Any significant systemic illness or unstable medical condition
Current use of Parkinson's medications, antipsychotic medications, anti-seizure medications, or anticholinergic medications
Current or lifetime diagnosis of a schizophrenia spectrum disorder, psychotic disorder, bipolar disorder type I \& II, cluster B personality disorders (antisocial, borderline, narcissistic, histrionic), eating disorders, as defined by the DSM-5-TR
Participation in other clinical studies involving neuropsychological measures being collected more than one time per year.
Reported use of other drugs (cocaine, opiates, methamphetamine, MDMA) in the past 60 days or test positive on a urine test for those drugs of abuse at baseline.
Report using more than 150mg of cannabis edible products per week.
Report using more than 7 grams of cannabis flower product (not including CBD) per week.
Recent history of, or meets criteria for major depression with suicidal ideation.
Reports use of medical CBD.
Liver function enzymes (AST, ALT) that are greater than 2x normal.
Currently taking medications known to be contraindicated with Epidiolex (buprenorphine, leflunomide, levomethadyl acetate, lomitapide, mipomersen, pexidartinib, propoxyphene, sodium oxybate, teriflunomide, clobazam, lamotrigine, valproate).
Pregnant at the time of study enrollment or unwilling to use contraception through the duration of the study (if not yet post-menopausal)
Individuals with potentially reversible causes of mild cognitive impairment (i.e., hypothyroidism, Vitamin B12 deficiency).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT05822362) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Mild Cognitive Impairment Treatment Options in Aurora, CO

If you're searching for mild cognitive impairment treatment options in Aurora, CO, this clinical trial (NCT05822362) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced mild cognitive impairment specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all mild cognitive impairment clinical trials near you to find additional studies recruiting in your area.

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