Fremont, CANCT07558668Now EnrollingIRB Ready

Moderate to Severe Atopic Dermatitis Clinical Trial in Fremont, CA

Access cutting-edge moderate to severe atopic dermatitis treatment through this clinical trial at a research site in Fremont. Study-provided care at no cost to qualified participants.

Sponsored by Sitryx Therapeutics Ltd

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Expert Care in Fremont

Access moderate to severe atopic dermatitis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related moderate to severe atopic dermatitis treatment provided free

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Check if you qualify for this moderate to severe atopic dermatitis clinical trial in Fremont, CA

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Why Participate?

  • No-Cost Study Care

  • Local to Fremont

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Fremont site if eligible
  4. 4Begin participation

About This Moderate to Severe Atopic Dermatitis Study in Fremont

The purpose of this study is to evaluate the study drug, SYX-5219, in a multi-part First-in-Human (FiH) study to be conducted in healthy volunteers and participants with Atopic Dermatitis (AD). The objectives of this study are to determine the safety, tolerability and levels of SYX-5219 in the blood and urine when SYX-5219 is given in each part of the study (SAD, MAD, Food Effect and Participants with AD). The study will be split into up to 3 parts as follows: * Part 1 - Single Ascending Dose (SAD) and Food Effect in healthy volunteers * Part 2 - Multiple Ascending Dose (MAD) in healthy volunteers * Part 3 - Multiple Dose in Participants with AD - enrolling up to 45 males and females with a confirmed diagnosis of AD of at least 6 months, evaluating multiple dose administrations of SYX-5219 or placebo daily over a period of 42 days.

Sponsor: Sitryx Therapeutics Ltd

Who Can Participate

Inclusion Criteria

Parts 1 \& 2
Healthy male and female participant, between ≥ 18 to ≤ 65 years of age, inclusive, with a BMI of body mass index (BMI) of 18-32 kg/m2.
Female participant of non-childbearing potential or female of childbearing potential that is sexually abstinent.
No clinically significant abnormalities in laboratory, vital signs or ECG measurements. Part 3
Male and female participants with clinically confirmed diagnosis of active AD, between ≥ 18 to ≤ 65 years of age, inclusive, with a BMI of body mass index (BMI) of ≤40 kg/m2.
Meet minimum AD entry criteria;
AD covering ≥10% of the body surface area (BSA) at screening and baseline.
Eczema Area and Severity Index (EASI) score ≥16 at screening and baseline.
Validated Investigator's Global Assessment (vIGA) score of ≥ 3 (moderate) at screening and baseline.
Peak Pruritus NRS score of ≥ 4 at screening and baseline.

Exclusion Criteria

Parts 1 \& 2 • Use of prescription or non-prescription drugs, including vitamins, herbal and dietary supplements within 35 days or 5 half-lives (whichever is longer) prior to the first dose of IMP. Part 3
Any clinically significant medical condition or physical/laboratory/ECG/vital signs abnormality that would, in the opinion of the Investigator, put the participant at undue risk.
Has medical history as stated in the main study exclusion criteria.
Received treatment(s) as stated in the main study exclusion criteria.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Fremont?

Yes, this clinical trial (NCT07558668) has an active research site in Fremont, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Moderate to Severe Atopic Dermatitis Treatment Options in Fremont, CA

If you're searching for moderate to severe atopic dermatitis treatment options in Fremont, CA, this clinical trial (NCT07558668) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Fremont research site is actively enrolling participants for this clinical trial. You'll receive care from experienced moderate to severe atopic dermatitis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all moderate to severe atopic dermatitis clinical trials near you to find additional studies recruiting in your area.

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