NCT07011914 · NYU Langone Health
Care in Multiple Sclerosis (MS)
What this study is about
This study is structured around three main aims. In Aim 1, investigators will conduct community-based participatory research (CBPR) to develop culturally tailored methods to assess childhood adversity in multiple sclerosis (MS).
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This study is structured around three main aims. In Aim 1, investigators will conduct community-based participatory research (CBPR) to develop culturally tailored methods to assess childhood adversity in multiple sclerosis (MS). Aim 2 will investigate the impact of childhood adversity on MS outcomes among individuals with relapsing-remitting MS (RRMS), among whom 70% belong to a group historically under-represented in MS research: Black, Hispanic, or poverty-impacted. Aim 2 procedures involve two visits that include a research blood draw and an MRI scan. In Aim 3, investigators will conduct interviews and surveys to explore environmental and social factors affecting quality of life for minority MS patients.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- aged ≥18-29 years
- diagnosis of RRMS (Fulfill international criteria for relapsing remitting (RRMS))
- 70% self-identifying as a Black, Hispanic, or poverty-impacted (up to 138% of the federal poverty level) individual,and
- fluent in English or Spanish. Aim 2 -
- aged ≥18-29 years
- diagnosis of RRMS (Fulfill international criteria for relapsing remitting (RRMS))
- 70% self-identifying as a Black, Hispanic, or poverty impacted, and
- fluent reading in English or Spanish
- Pediatric onset MS (MS onset before age 18 and age at time of enrollment is 18-25) OR adult-onset MS (MS onset at age 18 or older and age at time of enrollment is 19-29)
- Disease duration below 8 years Aim 3 - Aim 3 will enroll the first 20 participants from Aim 2 who meet the following criteria:
- completed at least 80% of study data in the cross-sectional study/Aim 2.
- a total of 70% must self-identify as Black, Hispanic, or meet criteria for poverty impacted.
- interviews will be evenly split between participants with high (top quartile) and low (bottom quartile) of PROMIS-10 scores.
Exclusion criteria
- Primary or Secondary Progressive MS
- Inability to consent.
- MS relapse within 30 days prior to study entry
- Other major neurologic or psychiatric illness
Where
- Birmingham, Alabama
- San Francisco, California
- Aurora, Colorado
- Boston, Massachusetts
- Cleveland, Ohio
- Houston, Texas
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced May 5, 2026 · Source of record for eligibility and locations