Tucson, AZNCT07224373Now EnrollingIRB Ready

Multiple Sclerosis Clinical Trial in Tucson, AZ

Access cutting-edge multiple sclerosis treatment through this clinical trial at a research site in Tucson. Study-provided care at no cost to qualified participants.

Sponsored by AstraZeneca

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Expert Care in Tucson

Access multiple sclerosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related multiple sclerosis treatment provided free

Apply for This Tucson Location

Check if you qualify for this multiple sclerosis clinical trial in Tucson, AZ

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Tucson

    Convenient for AZ residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Tucson site if eligible
  4. 4Begin participation

About This Multiple Sclerosis Study in Tucson

This trial is a Phase 1b, open-label, multi-center, clinical study of AZD0120, a BCMA/CD19 dual targeting CAR+ T-cell therapy, to evaluate the safety and tolerability in adult participants with Multiple Sclerosis.

Sponsor: AstraZeneca

Who Can Participate

Inclusion Criteria

Diagnosis of RMS according to the 2024 McDonald Criteria (Montalban et al 2025) or diagnosis of relapsing, active SPMS according to Lublin et al 2014.
Participants should have an EDSS of ≤ 6.5 at screening.
Evidence of active disease (clinical relapses and MRI activities within 2 years prior to screening), or intolerance, while on a high efficacy disease-modifying therapy for ≥ 6 months. PMS Cohort Specific Inclusion Criteria
Diagnosis of PPMS according to the 2024 McDonald Criteria (Montalban et al 2025) or non-relapsing SPMS according to Lublin et al 2014.
Participants must have an EDSS of ≥ 3.0 and ≤ 6.5 at screening.
Inadequate response ≥ 1 heDMT with ≥ 6 months treatment or intolerance.

Exclusion Criteria

Participants are excluded from the study if any of the following criteria apply:
Any prior CAR-T or CAR-NK cell exposure.
Underwent splenectomy within 12 months prior to signing the ICF.
Received a solid organ transplant at any time or on an active transplant waiting list.
Prior treatment with autologous hematopoietic stem cell transplantation or total lymphoid irradiation.
Cardiac conditions or any other significant cardiac condition that would present undue risk to the participant in the investigator's opinion:
Any other central nervous system disease including epilepsy, convulsive seizures, organic encephalopathy syndrome, non-MS related paralysis, aphasia, stroke, severe brain injury, dementia, Parkinson's disease or associated movement disorder, psychosis, CNS vasculitis, or any other neurological disease that may impact the ability to evaluate neurotoxicity. History of a seizure disorder even if the seizure disorder is well controlled with anti-epileptics.
Participant has significant psychiatric condition (active or history of).
History of other immune-mediated disease that required continued systemic immunosuppression/systemic disease-modifying agents.
Evidence of clinically significant bleeding or active bleeding diathesis within 90 days before screening
History of malignancy or ongoing treatment for prior malignancy.
Inborn error of immunity and/or primary immunodeficiency.
Seropositive for HIV or HTLV (including any history of HIV or HTLV).
Active viral (any etiology, HBV, HCV) hepatitis are excluded.
Major surgery within 4 weeks prior to apheresis or lymphodepletion or has surgery planned during the study or within 4 weeks after study treatment administration.
Pregnant, breastfeeding, or planning to become pregnant while enrolled in this study or within 1 year after receiving study treatment, whichever is longer.
Unwilling or unsafe to proceed with CSF exams based on coagulopathy or anatomy or other considerations in the judgment of the study investigator.
Any contraindications to LP.
Participants not willing, able, or are unsafe to take MRI scans as per protocol.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Tucson?

Yes, this clinical trial (NCT07224373) has an active research site in Tucson, AZ that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Multiple Sclerosis Treatment Options in Tucson, AZ

If you're searching for multiple sclerosis treatment options in Tucson, AZ, this clinical trial (NCT07224373) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Tucson research site is actively enrolling participants for this clinical trial. You'll receive care from experienced multiple sclerosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all multiple sclerosis clinical trials near you to find additional studies recruiting in your area.

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