NCT06631053 · Lance Bollinger
FIT Exercise in 30d of ULLS-induced Muscle Disuse
What this study is about
This study aims to determine how flywheel-based inertial training (FIT) implemented according to principles of velocity-based training (VBT) and High-Intensity Interval Training (HIIT) affects disuse-induced physical de-conditioning including loss of voluntary muscle strength, aerobic capacity, and balance regulation.
View original scientific description
This study aims to determine how flywheel-based inertial training (FIT) implemented according to principles of velocity-based training (VBT) and High-Intensity Interval Training (HIIT) affects disuse-induced physical de-conditioning including loss of voluntary muscle strength, aerobic capacity, and balance regulation.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Regularly engaging in aerobic exercise (\> 150min/wk) and resistance exercise (\>1 time per week) for the past 12 months
- Education greater than or equal to bachelor's degree (any field)
Exclusion criteria
- Waist circumference \< 55cm or \> 90cm (F) and \< 75cm or \> 100cm (M)
- Body mass index \< 18.5 or \> 29.9
- Shoe size \< 25 or \>29cm.
- Not regularly engaging in exercise for previous 12 months
- Tobacco use within previous 6 months
- Blood clotting disorder
- Heart arrhythmia
- Implanted device which could negatively be affected by electrical impulse or strong magnetic field such as pacemaker, internal defibrillator, or cochlear implant
- Diagnosed cardiovascular, pulmonary, renal, or metabolic disease
- Pregnancy (within previous 6 months)
- Oral contraceptive use (within previous three months)
- High resting blood pressure (\>140 systolic and/or \> 90 diastolic)
- Currently or previously undergone gender-affirming therapy (hormone therapy or sexual reassignment surgery)
- Low back or leg injury in previous 6 months
- Currently taking medication to assist with sleep
- Muscle, bone, or joint injury that limits physical activity within previous 6 months
- Neurological disorder which affects balance (such as multiple sclerosis or Parkinson's disease)
Where
- Lexington, Kentucky
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Oct 24, 2025 · Source of record for eligibility and locations