Iowa City, IANCT04800484Now EnrollingIRB Ready

Musculoskeletal Injury Clinical Trial in Iowa City, IA

Access cutting-edge musculoskeletal injury treatment through this clinical trial at a research site in Iowa City. Study-provided care at no cost to qualified participants.

Sponsored by University of Iowa

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Expert Care in Iowa City

Access musculoskeletal injury specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related musculoskeletal injury treatment provided free

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Check if you qualify for this musculoskeletal injury clinical trial in Iowa City, IA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Iowa City

    Convenient for IA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Iowa City site if eligible
  4. 4Begin participation

About This Musculoskeletal Injury Study in Iowa City

The proposed study evaluates the effect of ankle foot orthosis (AFO) heel height and stiffness on the forces and motion of the lower limb during over-ground walking in individuals who use an AFO for daily walking. Previous studies suggest that heel height and stiffness effect limb loading, but these data and the analysis techniques applied are limited. In this study, heel cushions with different height and stiffness's (4 conditions) will be placed in participants shoes and they will walk at controlled and self-selected speeds. Participants will also walk with their AFO as configured prior to enrollment, and with no AFO if possible. The proposed study will provide evidence that can be used by clinicians and researchers to align braces that most effectively improve function during every-day walking.

Sponsor: University of Iowa

Who Can Participate

Inclusion Criteria

Ages: 18-70
Daily AFO use to address unilateral, below knee functional deficits that result from limb injury or musculoskeletal disease (e.g. fracture, muscle and/or nerve injury, ankle arthritis)
Greater than 2 weeks using their current AFO
Ability to walk 50 feet without use of an assistive device (Cane, crutch, etc.)
Ability to walk at a slow to moderate pace
AFO fits into traditional footwear
Able to read and write in English and provide written informed consent GROUP 1 Patient

Exclusion Criteria

Pain \> 6/10 while walking during testing or an increase in pain during testing of \> 2/10.
Central Nervous System disorder or disease (e.g. Stroke, Cerebral Palsy, Spinal Cord Injury, or other conditions that result in lower limb spasticity).
Disorder or disease that affects peripheral nerve function (e.g. diabetes, Charcot Marie Tooth).
Limited contralateral lower limb function due to injury or neurological/musculoskeletal disorder.
Use of a hinged/articulating AFO (e.g. Plantar flexion stop, Dorsiflexion assist/stop, free motion), Charcot Restraint Orthotic Walker (CROW) boot, AFOs that restrict all motion in the ankle and foot.
Use of an AFO that crosses the knee (Knee brace)
Insufficient space in shoe to accommodate the tallest heel wedge and their AFO
Visual or hearing impairments that limit walking ability or could limit the ability to comply with instructions given during testing
Pregnancy - Per participant self-report. Due the expected small number of pregnant individuals, and resulting inability to account for its effect on resulting outcomes participants will be withdrawn from the study.
Body Mass index \> 40. GROUP 2 Patient Inclusion Criteria
Ages: 18-70
Daily AFO use to address below knee functional deficits that result from disease involving the peripheral nervous system (e.g. Charcot Marie Tooth, Multiple Sclerosis, diabetes)
Greater than 2 weeks using their current AFO (unilateral or bilateral)
Ability to walk 50 feet without use of an assistive device (Cane, crutch, etc.)
AFO fits into traditional footwear
Ability to walk at a slow to moderate pace
Able to read and write in English and provide written informed consent GROUP 2 Patient Exclusion Criteria
Pain \> 6/10 while walking or an increase in pain during testing of \> 2/10
Central Nervous System disorder or disease (e.g. Stroke, Cerebral Palsy, Spinal Cord Injury, or other conditions that result in lower limb spasticity)
Limited function due to limb injury (e.g. fracture, muscle and/or nerve injury)
Use of a hinged/articulating AFO (e.g. Plantar flexion stop, Dorsiflexion assist/stop, free motion), Charcot Restraint Orthotic Walker (CROW) boot, AFOs that restrict all motion in the ankle and foot.
Use of an AFO that crosses the knee (Knee brace)
Insufficient space in shoe to accommodate the tallest heel wedge and their AFO
Visual or hearing impairment that limit walking ability or limit the ability to comply with instructions given during testing
Pregnancy - Per participant self-report. Due the expected small number of pregnant individuals, and resulting inability to account for its effect on resulting outcomes participants will be withdrawn from the study
Body Mass index \> 40.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Iowa City?

Yes, this clinical trial (NCT04800484) has an active research site in Iowa City, IA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Musculoskeletal Injury Treatment Options in Iowa City, IA

If you're searching for musculoskeletal injury treatment options in Iowa City, IA, this clinical trial (NCT04800484) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Iowa City research site is actively enrolling participants for this clinical trial. You'll receive care from experienced musculoskeletal injury specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all musculoskeletal injury clinical trials near you to find additional studies recruiting in your area.

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