Baltimore, MDNCT07849231Now EnrollingIRB Ready

Myeloproliferative Neoplasms (MPNs) Clinical Trial in Baltimore, MD

Access cutting-edge myeloproliferative neoplasms (mpns) treatment through this phase 1 clinical trial at a research site in Baltimore. Study-provided care at no cost to qualified participants.

Sponsored by Damora Therapeutics

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Expert Care in Baltimore

Access myeloproliferative neoplasms (mpns) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related myeloproliferative neoplasms (mpns) treatment provided free

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Check if you qualify for this myeloproliferative neoplasms (mpns) clinical trial in Baltimore, MD

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Why Participate?

  • No-Cost Study Care

  • Local to Baltimore

    Convenient for MD residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Baltimore site if eligible
  4. 4Begin participation

About This Myeloproliferative Neoplasms (MPNs) Study in Baltimore

This is a multi-center, open-label, Phase 1/1b study designed to evaluate the safety, pharmacokinetics, immunogenicity, and preliminary efficacy of DMR-001 monotherapy in adult participants with CALR-mutated essential thrombocythemia (ET) and myelofibrosis (MF), and of DMR-001 in combination with ruxolitinib in participants with CALR-mutant MF.

Sponsor: Damora Therapeutics

Who Can Participate

Inclusion Criteria

Signed informed consent, which includes compliance with the requirements and restrictions listed in the ICF and the protocol.
Diagnosis/confirmation of ET or MF as defined in the protocol.
Documented CALR exon-9 mutation.
Willingness to undergo bone marrow biopsy and aspiration per the Schedule of Assessments.

Exclusion Criteria

Presence of any malignancy unless participant has been disease free for at least 2 years.
History of major bleeding or thrombosis within the last 3 months prior to study enrollment.
Prior hematopoietic stem cell transplantation or donor leukocyte infusion, or such transplantation or infusion is planned.
Participants with laboratory values exceeding protocol defined thresholds.
History of clinically significant or uncontrolled cardiac disease.
Active HBV, HCV or HIV.
Known hypersensitivity to DMR-001 or ruxolitinib or any of their components. Other protocol defined Inclusion/Exclusion Criteria may apply.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Baltimore?

Yes, this clinical trial (NCT07849231) has an active research site in Baltimore, MD that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Myeloproliferative Neoplasms (MPNs) Treatment Options in Baltimore, MD

If you're searching for myeloproliferative neoplasms (mpns) treatment options in Baltimore, MD, this clinical trial (NCT07849231) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Baltimore research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced myeloproliferative neoplasms (mpns) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all myeloproliferative neoplasms (mpns) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Baltimore, MD