Boston, MANCT04551482Now EnrollingIRB Ready

Obesity, Adolescent Clinical Trial in Boston, MA

Access cutting-edge obesity, adolescent treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Massachusetts General Hospital

Quick Self-Assessment

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Expert Care in Boston

Access obesity, adolescent specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related obesity, adolescent treatment provided free

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Check if you qualify for this obesity, adolescent clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Obesity, Adolescent Study in Boston

This is a randomized, double blind, placebo-controlled study of the effects of intranasal oxytocin in youths with obesity, ages 10-18 years old. Subjects will be randomized to receive intranasal oxytocin or placebo (1 spray per nostril, 4 times per day) for 12 weeks. Study visits include screening to determine eligibility, 2-part main study visits at baseline, week 8, and week 12, and safety check-in visits at weeks 1, and 4; phone calls at weeks 2, 6, and 10, with a safety follow-up visit 6 weeks after the last dose of study drug. Study procedures include appetite, behavioral, metabolic, and endocrine assessments.

Sponsor: Massachusetts General Hospital

Who Can Participate

Inclusion Criteria

Males and Females, 10-18 years
Obesity (BMI ≥95th percentile for age and gender)
Willingness to maintain current diet and lifestyle for the duration of study participation

Exclusion Criteria

Current substance abuse
Use of prescription or over-the-counter drugs or dietary/herbal supplements that may affect weight if dose increased in the three months preceding the baseline visit and/or if they plan to increase the dose during the 18 weeks of study participation.
Greater than 5kg weight loss over 3 months;
Follows a nonstandard diet (e.g., Paleo, Atkins, raw diet, macrobiotic diet)
Cardiovascular disease
Prolonged QT interval
Chronic inflammatory bowel disease and other inflammatory conditions
TSH \> 2.5 times upper limit of normal
Alanine transaminase (ALT) or aspartate transaminase (AST) \>2.5 times upper limit of normal
Creatinine \>1.5 mg/dl
Hyponatremia
Pregnancy/breastfeeding or refusal to use contraception not containing estrogen throughout the study if female and sexually active
MRI exclusion criteria such as the presence of a pacemaker or cerebral aneurysm clips
Weight \>450 lbs due to limits for MRI and DXA scanners
Type 1 Diabetes Mellitus or Type 2 Diabetes Mellitus if HbA1c \>8%
Active eating disorder

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT04551482) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obesity, Adolescent Treatment Options in Boston, MA

If you're searching for obesity, adolescent treatment options in Boston, MA, this clinical trial (NCT04551482) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obesity, adolescent specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obesity, adolescent clinical trials near you to find additional studies recruiting in your area.

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