NCT07231484 · University of Missouri-Columbia
Effects of Grape Consumption on the Immune-Gut Axis in Obesity
What this study is about
This study is investigating the benefits of whole freeze-dried grape powder consumption on the immune-gut axis in adults with obesity.
View original scientific description
This study is investigating the benefits of whole freeze-dried grape powder consumption on the immune-gut axis in adults with obesity.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Age: 30-45 years
- Obesity with BMI of 30-45 kg/m2
- Willingness to consume study foods
- Consistent diet and activity patterns for 4 weeks
- Weight stable (\<5kg change over last 3 months)
- Non-smoker \> 1 year or more
- Not currently consuming an extremely healthy diet
Exclusion criteria
- Study food allergies
- Regular consumption of grapes or grape-derived products
- Gastrointestinal disease and/or bariatric surgery
- Uncontrolled hypertension and blood pressure \>180/110
- Clinical Depression
- Illicit drug use
- History of alcohol or drug abuse
- Recent use of medications that affect immune function (e.g., corticosteroids)
- Recent consumption of antibiotics, prebiotics, probiotics, symbiotics, or dietary supplements containing fiber or phytochemicals
- Pregnant or lactating individuals
- HIV positivity
- Recent start of medications that affect metabolism or appetite
- Drug therapy for coronary artery disease, peripheral artery disease, congestive heart failure, or dyslipidemia
Where
- Columbia, Missouri
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Dec 30, 2025 · Source of record for eligibility and locations