Cary, NCNCT06734312Now EnrollingIRB Ready

Obesity and Obesity-related Medical Conditions Clinical Trial in Cary, NC

Access cutting-edge obesity and obesity-related medical conditions treatment through this clinical trial at a research site in Cary. Study-provided care at no cost to qualified participants.

Sponsored by Dr. Christopher McGowan

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Expert Care in Cary

Access obesity and obesity-related medical conditions specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related obesity and obesity-related medical conditions treatment provided free

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Check if you qualify for this obesity and obesity-related medical conditions clinical trial in Cary, NC

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Why Participate?

  • No-Cost Study Care

  • Local to Cary

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cary site if eligible
  4. 4Begin participation

About This Obesity and Obesity-related Medical Conditions Study in Cary

The purpose of this study is to assess the effect of gastric fundal mucosal ablation (GFMA) on weight trajectory following discontinuation of once-weekly semaglutide or tirzepatide in adults with obesity. In this study, GFMA will be performed on patients who have experienced \> 10% weight loss with GLP-1 therapy and who plan to discontinue use of GLP-1 medications for the duration of the study.

Sponsor: Dr. Christopher McGowan

Who Can Participate

Inclusion Criteria

Subjects aged 21-65
Body mass Index (BMI) ≥30 kilograms per square meter (kg/m²), or ≤45 kg/m²
Observed ≥ 10% TBWL with semaglutide or tirzepatide use for primary obesity therapy
Subject did not experience \>50% weight recurrence since discontinuation of semaglutide or tirzepatide
Maintained a stable dose of semaglutide or tirzepatide for a minimum of 12 weeks
Have recently discontinued or are planning to discontinue semaglutide or tirzepatide (≤ 24 weeks from last dose to time of study procedure)
No previous medical history of diabetes mellitus
Willing and able to participate in the study procedures
Understand and voluntarily sign the informed consent

Exclusion Criteria

Known diagnosis of type I or type II diabetes or a Hemoglobin A1c \> 6.5% at time of screening
Use of GLP-1 or GLP-1/GIP medication for the treatment of diabetes, rather than obesity.
Use of anticoagulation, antithrombotic agents, and/or NSAIDs that cannot be discontinued for a minimum of 12 weeks
Known bleeding diathesis that cannot be corrected through medical means.
History of decompensated end-organ disease
Unwillingness to abstain from the use of incretin mimetics during the study duration.
Unwillingness to abstain from the use of tobacco during the study duration
Patients on any medications or supplements including those that may influence cholecystokinin (CCK), glucose, growth hormone, insulin and/or somatostatin levels
History of any stomach manipulation (including repair of hiatal hernia or fundoplication) deemed unsafe by PI for GFMA
Active disordered eating
Patients who do not give their consent to the enrollment in the study or are incompetent, unconscious or unable to express their consent for any reason
Known diagnosis of gastroparesis or functional dyspepsia
Patients who are pregnant, who plan to become pregnant during study duration, or patients of child-bearing potential who refuse effective birth control methods (as approved by PI)
Active H. pylori infection or history of H pylori without treatment and confirmation of eradication
Active gastric ulceration.
Use of concomitant medications known to induce weight loss (including but not limited to liraglutide, phentermine, phentermine/topiramate, bupropion/naltrexone, metformin)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cary?

Yes, this clinical trial (NCT06734312) has an active research site in Cary, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obesity and Obesity-related Medical Conditions Treatment Options in Cary, NC

If you're searching for obesity and obesity-related medical conditions treatment options in Cary, NC, this clinical trial (NCT06734312) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cary research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obesity and obesity-related medical conditions specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obesity and obesity-related medical conditions clinical trials near you to find additional studies recruiting in your area.

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