Los Angeles, CANCT07806838Now EnrollingIRB Ready

Obesity & Overweight Clinical Trial in Los Angeles, CA

Access cutting-edge obesity & overweight treatment through this clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by University of California, Los Angeles

Quick Self-Assessment

See if you qualify for this Los Angeles location

Preparing your pre-screening questions…

Expert Care in Los Angeles

Access obesity & overweight specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related obesity & overweight treatment provided free

Apply for This Los Angeles Location

Check if you qualify for this obesity & overweight clinical trial in Los Angeles, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This Obesity & Overweight Study in Los Angeles

This pilot study will examine whether daily protein supplementation with or without a mixture of culinary spices can help preserve muscle mass and function in adults who are using GLP-1 medications for weight management. The study will include 75 adults who recently started a GLP-1 medication and are experiencing weight loss. Participants will be randomly assigned to one of three groups: standard of care, protein supplementation plus placebo capsules, or protein supplementation plus mixed spice capsules. The study will last 6 months. Researchers will compare changes in muscle mass and muscle function among the groups. Muscle mass will be measured using DEXA and D3-creatine enrichment. Muscle function will be assessed using walking, stair-climbing, and grip-strength tests. The study will also evaluate metabolic and inflammatory markers, body composition, dietary intake, physical activity, fatigue, sleep quality, quality of life, and other measures related to muscle health.

Sponsor: University of California, Los Angeles

Who Can Participate

Inclusion Criteria

Male or female ≥18 years of age at screening visit.
BMI \>27 kg/m² with weight-related conditions OR BMI \>30 kg/m².
Taking any FDA-approved GLP-1 medication, daily oral or weekly injectable, started up to three months ago, and experiencing at least 1 lb of weight loss per week.
Screening laboratory tests without significant abnormalities that might interfere with the study.

Exclusion Criteria

Consume spices regularly \>5 g/day.
Allergy or sensitivity to spices, or history of allergy or anaphylaxis of any kind.
Diagnosed with Type 2 diabetes.
Vegans/vegetarians.
Consuming protein, amino acid, or creatine supplements; occasional or infrequent use (1 serving per week or less) is allowed.
Milk protein allergy.
Severe lactose intolerance.
Current diagnosis of alcoholism or substance addiction.
Uncontrolled hypertension (systolic BP \>170 or diastolic BP \>100).
Eating a high-fiber/polyphenol diet or taking medication or dietary supplements that interfere with the absorption of polyphenols.
Frequently using prebiotics, probiotics, yogurt, and/or fiber supplements.
Pregnant, breastfeeding, or unwilling to practice birth control during study participation.
Presence of a condition or abnormality that, in the opinion of the investigator, would compromise participant safety or data quality.
Renal impairment measured as eGFR \<45 mL/min/1.73 m² (\<60 mL/min/1.73 m² in subjects treated with SGLT2i), according to the CKD-EPI creatinine equation as defined by KDIGO 2012.
Any unstable medical conditions or terminal diagnosis.
Unstable thyroid disease-not taking medication or medication dosage changed one or more times over the last 6 months. Stable thyroid disease on an unchanged prescription medication dose for ≥6 months is acceptable.
Current use of insulin or oral medication of metformin, SU, SGLT2i, glitazone, or DPP4 as single-agent therapy or combination oral agents.
Taking GLP-1 medications for more than 3 months.
Have a medical implant or other metal implant, including a pacemaker.
Unwilling to stay on a GLP-1 medication for 6 months or for the duration of study participation.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT07806838) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obesity & Overweight Treatment Options in Los Angeles, CA

If you're searching for obesity & overweight treatment options in Los Angeles, CA, this clinical trial (NCT07806838) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obesity & overweight specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obesity & overweight clinical trials near you to find additional studies recruiting in your area.

More Obesity Trials in Los Angeles, CA

See all obesity clinical trials recruiting in Los Angeles — not just this study.

Browse Obesity Trials in Los Angeles →

Browse More Trials by Condition

Obesity TrialsAll Conditions →

Ready to Join in Los Angeles?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Los Angeles, CA