Boston, MANCT05711758Now EnrollingIRB Ready

Obesity Clinical Trial in Boston, MA

Access cutting-edge obesity treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Christopher C. Thompson, MD, MSc

Quick Self-Assessment

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Expert Care in Boston

Access obesity specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related obesity treatment provided free

Apply for This Boston Location

Check if you qualify for this obesity clinical trial in Boston, MA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Obesity Study in Boston

Gastric myotomy has been performed for several years as a means of addressing chronic stenosis after sleeve gastrectomy and treating gastroparesis. The Pylorus Sparing Antral Myotomy (PSAM) technique has the opposite effect by leaving the pylorus intact and extending the myotomy proximally to the distal gastric body. PSAM was initially combined with ESG and shown to delay gastric emptying and provide greater weight loss without impacting tolerability (GCSI score) or the safety profile of the procedure (2 DDW GEM abstracts). PSAM has not been evaluated alone, without concomitant ESG. Since delayed gastric emptying alone is known to promote weight loss, it is thought that PSAM alone (without ESG) may provide similar efficacy, while reducing procedure time and adverse events. There have been no clinical studies that investigate the efficacy of PSAM independent of ESG. This pilot study aims to address this lack of information by evaluating the safety, tolerability, and short-term efficacy of PSAM, in addition to exploring its impact on gastric physiology. This will also provide data that may be used in designing a larger clinical trial.

Sponsor: Christopher C. Thompson, MD, MSc

Who Can Participate

Inclusion Criteria

subjects must be 18-70 years of age
eligible for endoscopic and surgical weight loss procedures
body mass index (BMI) greater than 35 kg/m2
Individuals must be in excellent mental health
able to understand and sign informed consent
available to return for all routine follow-up study visits

Exclusion Criteria

untreated H. pylori infection
gastroparesis
active smoking
an ongoing or a history of treatment with opioids in the last 12 months prior to enrollment
previous pyloromyotomy or pyloroplasty
gastrointestinal obstruction
severe coagulopathy
esophageal or gastric varices and/or portal hypertensive gastropathy
pregnancy or puerperium
any inflammatory disease of the gastrointestinal tract (including but not limited to severe (LA Grade C or D) esophagitis, active gastric ulceration, active duodenal ulceration, or specific inflammation such as Crohn's disease)
malignant or premalignant gastric diseases (such as high grade dysplasia, gastric cancer, or GIST)
severe cardiopulmonary disease or a history of coronary artery disease (including myocardial infarction within the past 6 months, poorly controlled hypertension, required use of NSAIDs)
history of gastrointestinal surgery
any serious health condition unrelated to their weight that would increase the risk of endoscopy
chronic abdominal pain
active psychological issues preventing participation in a lifestyle modification program
a known history of endocrine disorders affecting weight (uncontrolled hypothyroidism)
an inability to provide informed consent
use of any medication that may interfere with weight loss
use of any medication that may interfere with gastric emptying
any other condition which the investigator may deem as an impediment to compliance or hinder completion of the proposed study

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT05711758) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obesity Treatment Options in Boston, MA

If you're searching for obesity treatment options in Boston, MA, this clinical trial (NCT05711758) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obesity specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obesity clinical trials near you to find additional studies recruiting in your area.

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