NCT05143931 · Cedars-Sinai Medical Center
Avoid and Resist Strategies for Weight Management
What this study is about
The proposed randomly assigned controlled trial tests two self-regulatory approaches to improve intentional weight loss and diet quality in individuals with overweight or obesity: (1) an environmental control strategy (AVOID) and (2) an impulse control training strategy (RESIST).
View original scientific description
The proposed randomized controlled trial tests two self-regulatory approaches to improve intentional weight loss and diet quality in individuals with overweight or obesity: (1) an environmental control strategy (AVOID) and (2) an impulse control training strategy (RESIST).
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- (Main participants):
- Age 18 years or older
- BMI between 25-45 kg/m2
- Read, write, and speak English with acceptable visual acuity
- Has a household member (≥ 14 years) willing to complete three brief assessments over 12 months\
- \*Only applies to individuals who indicate they are cohabitating with at least one eligible household member Inclusion Criteria (Household participants):
- 14-years-old
- Parent consent for children \<18-years-old
- Willingness to complete assessments / measurements
Exclusion criteria
- (Main participants):
- Currently enrolled in weight loss interventions or undergoing bariatric surgery
- Pregnant women
- Individuals for whom weight loss may be contraindicated (e.g., unstable coronary artery disease, end-stage disease, active cancer treatment, uncontrolled insulin-dependent diabetes, portal hypertension, drug/alcohol abuse)
- Individuals with severe cognitive delays or visual/hearing impairment
- Individuals who are unable or unwilling to complete the study assessments / measurements Exclusion Criteria (Household participants):
- ≤ 14-years-old
- Individuals who are unable or unwilling to complete the study assessments / measurements
Where
- Los Angeles, California
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Feb 17, 2026 · Source of record for eligibility and locations