Lancaster, PANCT05071898Now EnrollingIRB Ready

Obesity Clinical Trial in Lancaster, PA

Access cutting-edge obesity treatment through this clinical trial at a research site in Lancaster. Study-provided care at no cost to qualified participants.

Sponsored by University of Maryland, Baltimore

Quick Self-Assessment

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Expert Care in Lancaster

Access obesity specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related obesity treatment provided free

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Check if you qualify for this obesity clinical trial in Lancaster, PA

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Why Participate?

  • No-Cost Study Care

  • Local to Lancaster

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Lancaster site if eligible
  4. 4Begin participation

About This Obesity Study in Lancaster

Overweight/obese otherwise healthy volunteers will be recruited from the Old Order Amish population in Lancaster County, PA. Lancaster County, PA. Pharmacodynamic responses to GLP1R agonist will be assessed by conducting frequently sampled intravenous glucose tolerance tests (FSIGT) both before and after semaglutide for six weeks. The proposal proposes two specific aims: 1. Specific Aim #1. To identify genetic variants associated with effects of a GLP1R agonist to enhance glucose-stimulated first phase insulin secretion in the two FSIGTs (before and after administration of drug). 2. Specific Aim #2. To identify genetic variants associated with the effect of a GLP1R agonist to accelerate the rate of glucose disappearance as assessed in the two FSIGTs (before and after administration of drug). Genotyping will be conducted using a high-density array with comprehensive coverage of DNA sequence variants. In addition, the analysis will leverage a global imputation panel generated from 1,025 Amish individuals.

Sponsor: University of Maryland, Baltimore

Who Can Participate

Inclusion Criteria

BMI greater than or equal to 27 kg/m2
Of Amish Descent

Exclusion Criteria

Woman of childbearing age who is sexually active
History of diabetes (HbA1c \> 6.5% or random glucose \>200 mg/dL)
Known allergy to semaglutide
Medical issues, which in the judgment of the research physician or PIs might increase the risk associated with participation in the study
eGFR \< 60 mL/min/1.73 sq. m.
Hematocrit \< 35%
TSH \< 0.4 o4 \> 5.5
AST or ALT in excess of 2X the upper limit of normal
Unable to discontinue a drug, vitamin, or nutritional supplement, which in the judgment of the research physician or PIs might alter the response to semaglutide
Personal or family history of medullary carcinoma of the thyroid or multiple endocrine neoplasia, type 2

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Lancaster?

Yes, this clinical trial (NCT05071898) has an active research site in Lancaster, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obesity Treatment Options in Lancaster, PA

If you're searching for obesity treatment options in Lancaster, PA, this clinical trial (NCT05071898) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Lancaster research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obesity specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obesity clinical trials near you to find additional studies recruiting in your area.

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See all obesity clinical trials recruiting in Lancaster — not just this study.

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Secure · Expert Care · Lancaster, PA