Is NCT06575738 recruiting in Aurora, CO?

Yes, NCT06575738 is currently recruiting participants at its Aurora, CO location. This obesity clinical trial is actively enrolling qualified participants.

How do I join the obesity clinical trial in Aurora?

To join this clinical trial in Aurora, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Aurora clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Obesity Clinical Trial in Aurora, CO

About This Obesity Study in Aurora

The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond weight loss alone. The study also plans to learn more about whether a medication (semaglutide) can help people 12 to 24 years old who, between 1 and 2 years after bariatric surgery, have not lost as much weight as expected.

Sponsor: University of Colorado, Denver

Who Can Participate

Inclusion Criteria

Signed and dated informed consent form

Willingness to comply with all study procedures and availability for the duration of the study

Male or female biological sex, age 12 through 24 years

In the preoperative pathway for vertical sleeve gastrectomy

Exclusion Criteria

Planned Roux-en-Y gastric bypass

Hypothalamic obesity

Type 2 Diabetes

Current use of oral glucocorticoids (i.e. within 10 days of baseline visit)

Current use of insulin Intervention/Treatment Phase Inclusion Criteria:

Signed and dated informed consent form

Status post vertical sleeve gastrectomy

Male or female biological sex, age 12 through 24 years

Meeting minimum nutrition goals

Obesity: age 12-17 years: BMI ≥95th%ile for age/sex \| age 18-24 years: BMI ≥ 30kg/m\^2

If entering the Intervention phase from the Observational phase: ≤20% BMI loss at 1 year postop

If entering the Intervention phase from the existing patient pool: ≤20% BMI loss at 1-2 years postop Exclusion Criteria:

Surgically correctable cause of suboptimal postoperative weight loss

Known hypersensitivity to any component of semaglutide

Personal or family history of medullary thyroid carcinoma

Personal history of multiple endocrine neoplasia type 2

Hypothalamic Obesity

Type 2 Diabetes

History of pancreatitis

Uncontrolled hypertension

Clinically significant arrhythmia or heart disease that could be exacerbated by increased heart rate

Malignant neoplasm within the last 5 years

Untreated thyroid disorder

Tanner Stage 1

Baseline alanine transaminase (ALT) or aspartate aminotransferase (AST) ≥ 5x upper limit of normal

Baseline Creatinine \>1.2mg/dL

Active treatment for bulimia nervosa

Active major psychiatric disorder limiting informed consent

Suicidal ideation of type 4 or 5 on Columbia-Suicide Severity Rating Scale (C-SSRS)

Intentional self-harm within the previous 1 month

Severe unmanaged depression, defined by Center for Epidemiological Studies Depression (CESD) score of 26 or greater and by clinical evaluation

Recent change to concomitant medications for hypertension, dyslipidemia, depression or anxiety (\<4 weeks prior to enrollment)

Use of oral glucocorticoids (within 10 days of baseline visit)

Use of metformin (within 3 months of baseline visit)

Use of insulin secretagogues (within 4 half-lives of the medication of baseline visit)

Current use of insulin

Use of anti-obesity medications (within 4 half-lives of the medication of baseline visit)

Current pregnancy

For females of reproductive potential: Plan to become pregnant in the next 8 months

For females of reproductive potential: Not on contraception (i.e. two forms of birth control for example oral birth control pills and condoms) for at least 1 month prior to enrollment and agreement to use these during study participation and for an additional 8 weeks after the final dose of study medication

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT06575738) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obesity Treatment Options in Aurora, CO

If you're searching for obesity treatment options in Aurora, CO, this clinical trial (NCT06575738) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obesity specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obesity clinical trials near you to find additional studies recruiting in your area.

Obesity Clinical Trial in Aurora, CO

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