Irvine, CANCT07497880Now EnrollingIRB Ready

Obesity Clinical Trial in Irvine, CA

Access cutting-edge obesity treatment through this clinical trial at a research site in Irvine. Study-provided care at no cost to qualified participants.

Sponsored by Kailera

Quick Self-Assessment

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Expert Care in Irvine

Access obesity specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related obesity treatment provided free

Apply for This Irvine Location

Check if you qualify for this obesity clinical trial in Irvine, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Irvine

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Irvine site if eligible
  4. 4Begin participation

About This Obesity Study in Irvine

The primary objective of this study is to determine the efficacy of oral KAI-7535 once daily compared with placebo on percent change in body weight in participants living with obesity or overweight, with at least 1 weight-related comorbidity, without diabetes mellitus. Efficacy in participants with type 2 diabetes mellitus will be evaluated. Safety and tolerability and other weight-related outcomes will be evaluated in both types of participants.

Sponsor: Kailera

Who Can Participate

Inclusion Criteria

For participants without diabetes mellitus at screening and on Day 1, BMI ≥30 kilograms/square meter (kg/m\^2) or BMI ≥27 kg/m\^2 and a previous diagnosis of at least 1 of the following:
Hypertension
Dyslipidemia
Obstructive sleep apnea
Cardiovascular disease
For participants living with type 2 diabetes mellitus and BMI ≥27 kg/m\^2 only:
Diagnosis of type 2 diabetes mellitus
On stable therapy for type 2 diabetes mellitus for at least 3 months prior to screening Key

Exclusion Criteria

For participants without diabetes:
Laboratory evidence of diabetes
Taking a concomitant medication for the indication of glycemic control
For participants living with type 2 diabetes mellitus only:
History of diabetic ketoacidosis or hyperosmolar state/coma within 1 year of screening
History of severe hypoglycemia or hypoglycemia unawareness within 1 year of screening
History of proliferative diabetic retinopathy, diabetic maculopathy, or nonproliferative diabetic retinopathy that required acute treatment
Started medications that may cause significant weight change within 3 months prior to screening, including tricyclic antidepressants, atypical antipsychotics, and mood stabilizers
Unstable weight defined as self-reported change in body weight exceeding 5% within 3 months prior to screening
Family or personal history of multiple endocrine neoplasia Type 2 or medullary thyroid carcinoma
Uncontrolled hypertension or unstable cardiovascular disease
History of chronic or acute pancreatitis
Known clinically significant gastric-emptying abnormality or chronic treatment with medications that directly affect gastrointestinal motility
History of suicide attempt
History of significant active or unstable major depressive disorder or other severe psychiatric disorder
Received treatment with semaglutide, tirzepatide, glucagon-like peptide-1 (GLP-1) receptor agonist, GLP-1/glucose-dependent insulinotropic polypeptide receptor agonist, or glucagon receptor agonist within the last 3 months prior to screening Note: Additional inclusion/exclusion criteria may apply, per protocol.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Irvine?

Yes, this clinical trial (NCT07497880) has an active research site in Irvine, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obesity Treatment Options in Irvine, CA

If you're searching for obesity treatment options in Irvine, CA, this clinical trial (NCT07497880) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Irvine research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obesity specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obesity clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Irvine, CA