Is NCT07558148 recruiting in Philadelphia, PA?

Yes, NCT07558148 is currently recruiting participants at its Philadelphia, PA location. This obsessive compulsive disorder (ocd) clinical trial is actively enrolling qualified participants.

Is participation in this Philadelphia clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Obsessive Compulsive Disorder (OCD) Clinical Trial in Philadelphia, PA

Q: How do I join the obsessive compulsive disorder (ocd) clinical trial in Philadelphia?

To join this clinical trial in Philadelphia, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

About This Obsessive Compulsive Disorder (OCD) Study in Philadelphia

The investigators will conduct a pilot study to evaluate the safety and feasibility of low-intensity focused ultrasound on obsessive-compulsive disorder (OCD) symptoms when delivered to subcortical brain targets. The investigators will use the ATTN201 device to deliver single sessions of unfocused and focused ultrasound to up to three brain targets over 4 study visits and assess the intervention through self-rated scales of OCD symptoms.

Sponsor: University of Pennsylvania

Who Can Participate

Inclusion Criteria

1\. Participants must be enrolled in the IRB #853085 study The inclusion criteria for the IRB #853085 study, which are also included in this trial are: In order to be eligible to participate in this study, an individual must meet all of the following criteria:

Adults aged 18-60 years old

Chronic OCD (5 years preceding date of enrollment), diagnosed as per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition guidelines (DSM-5)

Presence of obsessions, compulsions, or both time-consuming obsessions and compulsions that take more than one hour a day or cause significant distress or impairment in social, occupation, or other important areas of functioning Obsessive-compulsive symptoms that are not attributable to the physiological effects of a substance (e.g., a drug of abuse, a medication) or another medical condition

Disturbance not better explained by the symptoms of another mental disorder listed in the DSM-5 Severe OCD symptoms, as defined by Y-BOCS I score of 28 or higher, within two weeks prior to enrollment

Compulsions need to involve movement of the hands and/or arms so that the sleeve is able to detect participant's actions (cannot be solely mental or verbal compulsions)

Ability to understand procedure-related instructions and to complete study assessments in English, and ability to comply with protocol requirements (e.g., procedure visits, treatment schedule, follow-up visit schedule, evaluations, etc.), in the opinion of the Principal Investigator

Willingness and ability to provide written agreement to allow any and all forms of communication between the research team and treating clinician(s) 8 Willingness and ability to provide informed consent, in the opinion of the Principal Investigator

Exclusion Criteria

An individual who meets any of the following criteria will be excluded from participation in this study:

Unable to undergo MRI scan

Presence of metallic implants or devices or tattoos

Claustrophobia or severe anxiety

Inability to remain still for duration of scan

Inability to fit and wear the ATTN201 device for the entire Exclusion criteria for IRB study #853085 include:

Hearing loss that, in the opinion of the Principal Investigator, an audiologist, or a treating physician, is likely to affect the subject's ability to comply with all of the requirements of the study, or may affect the integrity of the study data

Pregnancy - this is an exclusion criterion because we will be intentionally increasing anxiety in participants to evaluate optimal strategies to provoke distress and then promote relaxation

Any past or present medical condition, disease, disorder, or injury that, in the opinion of the Principal Investigator, may reduce or hinder the subject's ability to fully comply with all study requirements for the duration of the study or may impact, compromise, or affect the integrity of the data or results of the study.

Have a previous injury or surgery which could affect the nerve distribution

Have nerve damage (neuropathy)

Have a diagnosed neuromuscular disorder

Have a pacemaker

Have a history of skin allergies, psoriasis eczema, dermatitis, or other skin inflammation conditions

Compulsions cannot be completely mental or verbal actions, such as repeating words, counting objects, or performing mental rituals, and cannot involve only facial muscles/actions such as blinking or staring

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Philadelphia?

Yes, this clinical trial (NCT07558148) has an active research site in Philadelphia, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obsessive Compulsive Disorder (OCD) Treatment Options in Philadelphia, PA

If you're searching for obsessive compulsive disorder (ocd) treatment options in Philadelphia, PA, this clinical trial (NCT07558148) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Philadelphia research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obsessive compulsive disorder (ocd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obsessive compulsive disorder (ocd) clinical trials near you to find additional studies recruiting in your area.

Obsessive Compulsive Disorder (OCD) Clinical Trial in Philadelphia, PA

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