NCT07449195 · Memorial Sloan Kettering Cancer Center
A Study Comparing Two Optical Coherence Tomography Devices in People With Ocular Tumors
What this study is about
The purpose of this study is to compare two devices used for optical coherence tomography (OCT). OCT is a noninvasive imaging (scanning) method that uses reflected light to create pictures of the back of the eye, and doctors can use OCT to detect and monitor different types of cancer
View original scientific description
The purpose of this study is to compare two devices used for optical coherence tomography (OCT).
Interventions
DIAGNOSTIC_TEST
Intalight Dream OCT
This is a next-generation swept-source device that has a faster imaging speed and higher sensitivity than the previous generation of frequency-domain OCT devices, which serve as the current standard of care devices.
DIAGNOSTIC_TEST
Heidelberg Spectralis OCT
This is the standard of care for optical imaging.
Primary outcome measures
Image quality for participants
Time frame: Up to 1 year
Evaluated by next-generation swept-source OCT versus standard OCT for imaging of the eye and any relevant ocular tumors.
Field of view for participants
Time frame: Up to 1 year
Evaluated by next-generation swept-source OCT versus standard OCT for imaging of the eye and any relevant ocular tumors.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Age ≥18 years.
- At least 1 eye that has an intraocular or ocular surface tumor.
- The presence of a natural crystalline lens or intraocular lens.
- Pupils that can dilate up to at least 3 mm in the study eyes.
- The absence of opaque natural crystalline lenses or the presence of any ocular disease that prevents the view of the retina for imaging.
- Patients must be able to fixate on the imaging target.
- Patients must be able to sit still for a period of time (approximately 2 minutes).
Exclusion criteria
- Does not meet ALL of the above conditions
Where
- Basking Ridge, New Jersey
- Middletown, New Jersey
- Montvale, New Jersey
- Commack, New York
- Harrison, New York
- New York, New York
- Uniondale, New York
Collaborators
Intalight, Inc
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced May 13, 2026 · Source of record for eligibility and locations