Largo, MDNCT06293469Now EnrollingIRB Ready

Open Tibia Fracture Clinical Trial in Largo, MD

Access cutting-edge open tibia fracture treatment through this clinical trial at a research site in Largo. Study-provided care at no cost to qualified participants.

Sponsored by Johns Hopkins University

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Expert Care in Largo

Access open tibia fracture specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related open tibia fracture treatment provided free

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Check if you qualify for this open tibia fracture clinical trial in Largo, MD

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Largo

    Convenient for MD residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Largo site if eligible
  4. 4Begin participation

About This Open Tibia Fracture Study in Largo

The goal of this randomized controlled trial is to determine if accelerated flap coverage compared to standard flap coverage timing leads to improved infection-related complications in patients with open fractures and/or dislocations below the knee. Eligible patients will be randomized to receive either a flap within a goal of 72 hours of injury or standard of care flap timing for the institution. The primary outcome will be a composite outcome to evaluate clinical status 6 months after randomization. Components of the composite outcome will be hierarchically assessed in the following order: 1) all-cause mortality, 2) amputation related to injury, 3) re-operation for infection and/or flap complication (flap compromise, partial and/or complete flap failure), and 4) days in hospital, defined as days in an acute in-patient hospital (i.e., not rehab or nursing facility).

Sponsor: Johns Hopkins University

Who Can Participate

Inclusion Criteria

Patients 18 years of age or older.
Severe lower extremity open fracture and/or dislocation below the knee requiring an acute flap for management of the musculoskeletal injury.
Will have all planned flap surgeries performed by a participating surgeon or delegate.
Able to be randomized within 48 hours of injury. The

Exclusion Criteria

Site is unable to implement the accelerated flap protocol due to local logistics.
Primary amputation anticipated prior to attempted flap for management of the injury.
Critical limb ischemia that requires re-vascularization for limb perfusion.
Chronic or acute infection at or near the musculoskeletal injury site at the time of initial injury surgery.
Burns at the musculoskeletal injury site.
Incarceration.
Expected injury survival of less than 12 months.
Terminal illness with expected survival of less than 12 months.
Currently enrolled in a trial that does not permit co-enrollment.
Declined to provide informed consent.
Unable to obtain informed consent due to language barriers.
Unable to obtain informed consent because a legally authorized representative was unavailable.
Anticipated problems, in the judgment of research personnel, with maintaining follow-up with the patient.
Prior enrollment in the trial.
Eligible patient or LAR was not approached within screening window (missed participant).
Other reason to exclude the patient, as approved by the Principal Investigators.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Largo?

Yes, this clinical trial (NCT06293469) has an active research site in Largo, MD that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Open Tibia Fracture Treatment Options in Largo, MD

If you're searching for open tibia fracture treatment options in Largo, MD, this clinical trial (NCT06293469) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Largo research site is actively enrolling participants for this clinical trial. You'll receive care from experienced open tibia fracture specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all open tibia fracture clinical trials near you to find additional studies recruiting in your area.

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