Stanford, CANCT06208631Now EnrollingIRB Ready

Osteoarthritis, Knee Clinical Trial in Stanford, CA

Access cutting-edge osteoarthritis, knee treatment through this clinical trial at a research site in Stanford. Study-provided care at no cost to qualified participants.

Sponsored by Stanford University

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Expert Care in Stanford

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related osteoarthritis, knee treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Stanford

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Stanford site if eligible
  4. 4Begin participation

About This Osteoarthritis, Knee Study in Stanford

This study investigates how well individuals with knee osteoarthritis can learn to alter their calf muscle activation using haptic biofeedback while walking and evaluates how these changes affect knee loading. Prior research has utilized musculoskeletal simulations to determine that reducing the activation of one of the calf muscles, the gastrocnemius, can have a large impact on reducing knee loading. However, this has not been tested in individuals with knee osteoarthritis. In this study, participants will be trained to alter the activation of their gastrocnemius muscle, by receiving haptic feedback after each step. The feedback will indicate how the participant changed their muscle activation relative to baseline. Some participants will train on a treadmill in the laboratory for up to two sessions, with 30 minutes of walking with feedback in each session. If a participant can learn to adjust their muscle activation in the first training session, they will be able to complete the second training session. Other participants will train outside the laboratory for one session with 30 minutes of walking with feedback to investigate changes in knee loading while using the new walking strategy during over-ground walking. The movement data collected during the training sessions will be used as inputs to computer simulations of the musculoskeletal system to determine if walking with the new muscle activation strategy reduces knee loading.

Sponsor: Stanford University

Who Can Participate

Inclusion Criteria

Medial and/or lateral compartment knee osteoarthritis
Diagnosed with knee osteoarthritis of at least six months duration
Ambulatory without aids
Able to walk for at least 60 minutes
Typical pain rating of 1-4 on scale of 0-10
Able to reduce gastrocnemius muscle activation by 10% from baseline

Exclusion Criteria

History of symptomatic arthritis in lower limb joints other than the knees
Replacement of any lower extremity joint
Symptoms originating from the patellofemoral joint
Body mass index equal to or greater than 35
Nerve or muscle disease associated with walking difficulty
History of rheumatoid arthritis, gout, or autoimmune disease
History of lower limb fracture or surgery requiring hospitalization

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Stanford?

Yes, this clinical trial (NCT06208631) has an active research site in Stanford, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Osteoarthritis, Knee Treatment Options in Stanford, CA

If you're searching for osteoarthritis, knee treatment options in Stanford, CA, this clinical trial (NCT06208631) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Stanford research site is actively enrolling participants for this clinical trial. You'll receive care from experienced osteoarthritis, knee specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all osteoarthritis, knee clinical trials near you to find additional studies recruiting in your area.

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