Boston, MANCT05946044Now EnrollingIRB Ready

Osteoarthritis, Knee Clinical Trial in Boston, MA

Access cutting-edge osteoarthritis, knee treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Wake Forest University

Quick Self-Assessment

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Expert Care in Boston

Access osteoarthritis, knee specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related osteoarthritis, knee treatment provided free

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Check if you qualify for this osteoarthritis, knee clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Osteoarthritis, Knee Study in Boston

The goal of this study is to establish the efficacy of an intervention of dietary weight loss, exercise, and weight-loss maintenance for knee Osteoarthritis (OA) prevention in adult females aged ≥ 50 years with obesity and no or infrequent knee pain. The primary aim is to compare the effects of a dietary weight loss, exercise, and weight-loss maintenance to an attention control group in preventing the development of structural Magnetic Resonance Imaging (MRI) knee OA. Secondary aims will determine the intervention effects on pain, mobility, health-related quality of life, knee joint compressive forces, inflammatory measures, weight loss, exercise self-efficacy, and cost-effectiveness of this intervention.

Sponsor: Wake Forest University

Who Can Participate

Inclusion Criteria

BMI ≥ 30 kg/m2
An eligible knee will have no OA by xray and MRI
No or infrequent knee pain (\< 15 days/month) in the same knee

Exclusion Criteria

symptomatic or severe coronary artery disease
unable to walk without a device
type 1 diabetes
active treatment for cancer
during the past 12 months knee fracture, anterior cruciate ligament (ACL), medial collateral ligament (MCL), or meniscus injury with or without surgical repair
knee injection during the past 6 months
bilateral knee OA by x-ray Kellgren-Lawrence (KL) ≥ 2
bilateral knee OA by MRI
bilateral symptomatic knee OA (frequent bilateral knee pain \> 15 days per month)
BMI\< 30.0 kg/m2
claustrophobia
contraindication to MRI including body weight \> 300 lbs or knee coil does not fit
unwillingness or inability to change eating and physical activity habits due to environment
cannot speak and read English
planning to leave area \> 2 months during the 48-month intervention period

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT05946044) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Osteoarthritis, Knee Treatment Options in Boston, MA

If you're searching for osteoarthritis, knee treatment options in Boston, MA, this clinical trial (NCT05946044) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced osteoarthritis, knee specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all osteoarthritis, knee clinical trials near you to find additional studies recruiting in your area.

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