NCT07129226 · Case Comprehensive Cancer Center
Musculoskeletal Cancers Remote Monitoring and Care
What this study is about
This study aims to evaluate how walking stability and the ability to perform daily activities change during cancer treatment, and whether a smartwatch can detect these changes. The goal is to develop proactive, personalized tools that automatically monitor treatment response and predict potential complications.
View original scientific description
This study aims to evaluate how walking stability and the ability to perform daily activities change during cancer treatment, and whether a smartwatch can detect these changes. The goal is to develop proactive, personalized tools that automatically monitor treatment response and predict potential complications. To support future implementation, the study will assess the feasibility of wearing a smartwatch for at least 12 hours per day, using a mobile application, and completing weekly questionnaires among patients with primary osteosarcoma or metastatic bone disease.
Interventions
OTHER
Smart Watch
Participants will be asked to wear the smartwatch daily, for at least 12 hours per day during the 12-week study period, with breaks to recharge the watch as needed.
Primary outcome measures
Adherence Rate post surgery in patients with sarcoma of the lower extremity or pelvis
Time frame: 3 months
Adherence in each case involves averaging ≥ 12h/day wear time and completion in ≥10 out of 12 weeks of the TESS instrument
e-QOL post-surgery in patients with sarcoma of the lower extremity or pelvis
Time frame: 3 months
Adherence Rate post surgery in patients with metastatic bone disease of the lower extremity or pelvis
Time frame: 3 months
Adherence in each case involves averaging ≥ 12h/day wear time and completion in ≥10 out of 12 weeks of the TESS instrument
e-QOL post-surgery in patients with metastatic bone disease of the lower extremity or pelvis
Time frame: 3 months
Adherence Rate post-radiation in patients with metastatic bone disease of the lower extremity or pelvis
Time frame: 3 months
Adherence in each case involves averaging ≥ 12h/day wear time and completion in ≥10 out of 12 weeks of the TESS instrument
e-QOL post-radiation in patients with metastatic bone disease of the lower extremity or pelvis
Time frame: 3 months
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- primary sarcoma or metastatic bone disease of the lower extremities or pelvis.
- undergoing evaluation for (or have recently undergone) non-surgical or surgical intervention.
- recent history of home ambulation.
Exclusion criteria
- under 18 years of age at the time of study enrolment
- inability to comprehend consent form and give informed consent
- no access to a smartphone (iOS or Android) to interface with watch application
- tattoos located on the skin of the wrist or forearm where the watch will be placed or other skin conditions preventing adequate sensor function
- amputation or other disease of the arm or skin that prevents wear of a smart-watch device
- inability to tolerate watch for at least 12 hours per day on at least 80% of days in a four-week period
Where
- Cleveland, Ohio
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Aug 6, 2026 · Source of record for eligibility and locations