Chicago, ILNCT06235125Now EnrollingIRB Ready

Osteosarcoma Clinical Trial in Chicago, IL

Access cutting-edge osteosarcoma treatment through this phase 1 clinical trial at a research site in Chicago. Study-provided care at no cost to qualified participants.

Sponsored by Ann & Robert H Lurie Children's Hospital of Chicago

Quick Self-Assessment

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Expert Care in Chicago

Access osteosarcoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related osteosarcoma treatment provided free

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Check if you qualify for this osteosarcoma clinical trial in Chicago, IL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Chicago

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chicago site if eligible
  4. 4Begin participation

About This Osteosarcoma Study in Chicago

Pediatric subjects aged 6-17 with biopsy confirmed cancer and imaging findings suspicious for pulmonary metastatic disease scheduled to undergo pulmonary metastasectomy via and open or minimally invasive approach.

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Who Can Participate

Inclusion Criteria

Patients 6-17 years of age at the time of study enrollment
Willingness of research participant or legal guardian/representative to give written informed consent
Willingness of patients (subjects) age 12-17 to provide written adolescent assent
Patient weight greater than or equal to 20 kg
Histologically confirmed diagnosis of osteosarcoma, synovial sarcoma, hepatoblastoma, rhabdomyosarcoma, Ewing sarcoma, Wilms tumor or other non-rhabdomyosarcoma soft tissue sarcoma
Imaging findings highly suspicious for pulmonary metastatic disease based on CT, PET-CT or other imaging and warranting pulmonary surgery based on the judgment of the treating team. At least one nodule ≥4mm measured by preoperative imaging.
Female (assigned female at birth) participant is not pregnant and agrees to an acceptable form of contraception from the time of consent through 30 days after study intervention. Confirmed abstinence is an acceptable form of contraception.
Female (assigned female at birth) participant must agree to not donate ova from time of consent until 30 days after study intervention
Male (assigned male at birth) participant must agree to not donate sperm from time of consent until 30 days after study intervention.

Exclusion Criteria

Any medical condition that in the opinion of the investigators could potentially jeopardize the safety of the subject
History of anaphylactic reactions to products containing indocyanine green for near infrared imaging. Subjects with a medical history of 'idiopathic anaphylaxis' will also be excluded.
History of allergy to any of the components of CYTALUX™ (PAFOLACIANINE) INJECTION
Presence of any psychological, familial, sociological condition or geographical challenges potentially hampering compliance with the study protocol or follow-up schedule
Impaired renal function defined as eGFR\< 50 mL/min/1.73m2
Impaired liver function defined as values \> 3x the upper limit of normal (ULN) for alanine aminotransferase (ALT) or aspartate aminotransferase (AST), alkaline phosphatase (ALP), or \>2x ULN for total bilirubin except in subjects with Gilbert's syndrome.
Patient unable or unwilling to discontinue folate, folic acid, or folate-containing supplements 48 hours before study drug administration
History of drug-related serious adverse event with prior Cytalux administration will be an exclusion for re-enrollment for contralateral surgery (see section 5.7).
Participants will be excluded if their 12th or 18th birthday would occur during study participation
Male sex at birth and commitment to acceptable form of contraception from time of consent through 30 days after study intervention with confirmed abstinence as an acceptable form of contraception as an inclusion criterion.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chicago?

Yes, this clinical trial (NCT06235125) has an active research site in Chicago, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Osteosarcoma Treatment Options in Chicago, IL

If you're searching for osteosarcoma treatment options in Chicago, IL, this clinical trial (NCT06235125) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chicago research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced osteosarcoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all osteosarcoma clinical trials near you to find additional studies recruiting in your area.

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