Orange, CANCT04520139Now EnrollingIRB Ready

Ovarian Cancer Clinical Trial in Orange, CA

Access cutting-edge ovarian cancer treatment through this phase 1/2 clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by University of California, Irvine

Quick Self-Assessment

See if you qualify for this Orange location

Preparing your pre-screening questions…

Expert Care in Orange

Access ovarian cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related ovarian cancer treatment provided free

Apply for This Orange Location

Check if you qualify for this ovarian cancer clinical trial in Orange, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Ovarian Cancer Study in Orange

This is a phase I, dose-escalation and phase II dose-expansion clinical trial determining the maximum tolerated dose (MTD) and safety and tolerability of adding N-Acetyl-Cysteine (NAC) to ovarian cancer patients who are receiving a platinum-based therapy (PBT). This study will investigate whether NAC will mitigate chemotherapy-related cognitive impairment (CRCI).

Sponsor: University of California, Irvine

Who Can Participate

Inclusion Criteria

Post-menopausal females (as defined by lack of menstruation for 12 months or status post oophorectomy)
Histologic or pathologic diagnosis of stage III-IV epithelial ovarian, fallopian tube, or primary peritoneal cancer
Eastern Cooperative Oncology Group (ECOG) ≤2
Life expectancy \> 1 year
Status post cytoreductive surgery for ovarian cancer or with planned cytoreductive surgery if treated with neoadjuvant chemotherapy
Prescribed a minimum of six cycles of platinum-based chemotherapy
Adequate organ function as defined below:
Hemoglobin \> 9 g/dL
Leukocytes \>1,500/mcl
Absolute Neutrophil Count \> 1,000/mcL
Platelets \> 125,00/mcL
total bilirubin Within normal institutional limits
Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) \< 2.5 x institutional upper limit of normal
Serum creatinine \< 1.5 mg/dL.

Exclusion Criteria

Prior history of any cancer (other than non-melanoma skin cancer)
Chemotherapy, radiation therapy, or erythropoietin treatment within the last 6 months
Prior severe head injury
Has a history of dementia or other neurodegenerative disorders
Has an uncontrolled, treatment-resistant depression or other severe psychiatric illnesses
Presence of known brain metastases
Has an active infection requiring treatment
Known immunosuppressive disease
Has active systemic autoimmune diseases such as lupus
Receipt of systemic immunosuppressive therapy
Known human immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
Pregnant of breastfeeding.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT04520139) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Ovarian Cancer Treatment Options in Orange, CA

If you're searching for ovarian cancer treatment options in Orange, CA, this clinical trial (NCT04520139) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced ovarian cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all ovarian cancer clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Orange, CA