Winston Salem, NCNCT05674799Now EnrollingIRB Ready

Overweight or Obesity Clinical Trial in Winston Salem, NC

Access cutting-edge overweight or obesity treatment through this clinical trial at a research site in Winston Salem. Study-provided care at no cost to qualified participants.

Sponsored by Wake Forest University Health Sciences

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Expert Care in Winston Salem

Access overweight or obesity specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related overweight or obesity treatment provided free

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Check if you qualify for this overweight or obesity clinical trial in Winston Salem, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Winston Salem

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Winston Salem site if eligible
  4. 4Begin participation

About This Overweight or Obesity Study in Winston Salem

The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in childbearing years. The investigators will recruit 360 women aged 18-39 years with overweight/obesity who are not currently pregnant, but likely to conceive within 24 months. Women will be randomized to NDPP-NextGen or a usual care control group. The NDPP-NextGen group will participate in the adapted NDPP online group class across 12 months, and the control group will get a packet of information about how to be healthy before, during and after pregnancy. The main goals of the study are: 1. to assess effects of NDPP-NextGen on pre-pregnancy blood sugar and early pregnancy BMI 2. to assess effects of NDPP-NextGen on weight gain and behavioral outcomes during pregnancy 3. to explore effects of NDPP-NextGen on infant's percentage of fat tissue at birth All participants will complete up to 4 research visits: baseline, conception, mid-pregnancy, and delivery. These visits will include: 1. Questionnaires about health, diet, activity, smoking, self-confidence, and depression 2. Body size measurements 3. Fasted blood draws Participants will also be asked to weigh themselves weekly using home scales that are connected to the research database. At the delivery visit, investigators will measure the baby's body size and collect a cord blood sample.

Sponsor: Wake Forest University Health Sciences

Who Can Participate

Inclusion Criteria

Established patient at Denver Health or Atrium Health Wake Forest Baptist
Biologically female (inclusive of all gender identities)
Aged 18-39 years
English- or Spanish-speaking
BMI ≥25 kg/m2 (≥23 kg/m2 if Asian race)
Activities that lead to pregnancy in past 3 months
Interested in pregnancy within 24 months, including:
High interest (actively trying to conceive)
General interest (not actively trying but wanting to become pregnant in the foreseeable future)
Neutral interest (not planning pregnancy or using contraception for religious reasons)

Exclusion Criteria

Currently pregnant
Non-gestational diabetes (type 1, type 2)
Long-acting contraceptives (intrauterine device, implant, injection) with plans to continue for \>1 year (barrier \& short-acting hormonal contraception permitted given ease of discontinuing to facilitate pregnancy)
Medical procedures (e.g., tubal ligation, hysterectomy) or conditions that impede pregnancy
Documented infertility or unsuccessfully trying to conceive for ≥12 months
Prior participation in the NDPP
History of bariatric surgery
Use of GLP-1s in last year
Currently receiving clinical obesity treatment

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Winston Salem?

Yes, this clinical trial (NCT05674799) has an active research site in Winston Salem, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Overweight or Obesity Treatment Options in Winston Salem, NC

If you're searching for overweight or obesity treatment options in Winston Salem, NC, this clinical trial (NCT05674799) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Winston Salem research site is actively enrolling participants for this clinical trial. You'll receive care from experienced overweight or obesity specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all overweight or obesity clinical trials near you to find additional studies recruiting in your area.

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