Lebanon, NHNCT04678895Now EnrollingIRB Ready

Painful Diabetic Neuropathy Clinical Trial in Lebanon, NH

Access cutting-edge painful diabetic neuropathy treatment through this clinical trial at a research site in Lebanon. Study-provided care at no cost to qualified participants.

Sponsored by Dartmouth-Hitchcock Medical Center

Quick Self-Assessment

See if you qualify for this Lebanon location

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Expert Care in Lebanon

Access painful diabetic neuropathy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related painful diabetic neuropathy treatment provided free

Apply for This Lebanon Location

Check if you qualify for this painful diabetic neuropathy clinical trial in Lebanon, NH

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Lebanon

    Convenient for NH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Lebanon site if eligible
  4. 4Begin participation

About This Painful Diabetic Neuropathy Study in Lebanon

Diabetes affects more than 30 million people in the United States and is a leading cause of morbidity. Over 25% diabetics also suffer from debilitating painful diabetic neuropathy in the lower legs and feet. This pain can be severe, difficult to control, and have a significant negative impact on quality of life. Opioid medications have historically been a mainstay of treatment for this pain, despite the risks. As the death toll from the U.S. opioid epidemic continues to rise, the need for quality alternative non-opioid medications to treat pain becomes more urgent. One of these potential medications is Low-Dose Naltrexone (LDN). This drug is reported to work by enhancing the body's natural pain relieving mechanisms and decreases inflammation by targeting specific cells called microglia which have been shown to influence chronic pain. LDN has been shown to be a safe medication with minimal side effects. Its efficacy has been demonstrated in other painful conditions but has never been fully studied for treating painful diabetic neuropathy. The goal of this randomized, placebo-controlled trial is to determine if LDN is effective for treating the pain caused by diabetic neuropathy. LDN's mechanism of action is well suited to treating painful diabetic neuropathy, and LDN shows significant promise as a safe, non-opioid alternative that can decrease pain and improve quality of life for those suffering from this painful condition.

Sponsor: Dartmouth-Hitchcock Medical Center

Who Can Participate

Inclusion Criteria

Diagnosis of Painful Diabetic Neuropathy (PDN) for \>6 months
Has failed at least one prior standard treatment for PDN (Gabapentin, duloxetine, etc)
No other known causes of lower extremity neuropathic pain
Subjects capable of giving informed consent
Greater than 18 years of age
Stable on all current non-opioid pain medication for at least 1 month
English as primary language

Exclusion Criteria

Known allergy to naltrexone or naloxone
Presence of known causes of lower extremity neuropathic pain not attributed to PDN
Active substance use disorder or alcohol use disorder as defined by DSM-V (The Diagnostic and Statistical Manual of Mental Disorders)
Current treatment for substance use disorder or alcohol use disorder
Current opioid therapy or on opioid therapy within the past 1 month

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Lebanon?

Yes, this clinical trial (NCT04678895) has an active research site in Lebanon, NH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Painful Diabetic Neuropathy Treatment Options in Lebanon, NH

If you're searching for painful diabetic neuropathy treatment options in Lebanon, NH, this clinical trial (NCT04678895) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Lebanon research site is actively enrolling participants for this clinical trial. You'll receive care from experienced painful diabetic neuropathy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all painful diabetic neuropathy clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Lebanon, NH