NCT06423963 · H. Lee Moffitt Cancer Center and Research Institute
Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer
What this study is about
The purpose of the study is to examine the feasibility and acceptability of an exercise and nutrition "prehabilitation" program for patients preparing for pancreatic cancer resection (removal).
View original scientific description
The purpose of the study is to examine the feasibility and acceptability of an exercise and nutrition "prehabilitation" program for patients preparing for pancreatic cancer resection (removal).
Interventions
BEHAVIORAL
Physical Activity
Each participant will receive a Fitbit device with instruction and encouragement to self-monitor physical activity using step counts.
BEHAVIORAL
Nutrition Counseling
Participants will receive nutritional counseling with a registered dietician.
BEHAVIORAL
Resistance Training
Participants will engage in progressive, full-body resistance training based on American College of Sports Medicine (ACSM) guidelines.
Primary outcome measures
Feasibility and acceptability of PA/N and RT/N programs
Time frame: Up to 16 weeks
The number of participants who complete T1 and T0 measures.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Age 18 years or older
- Biopsy-proven pancreatic ductal adenocarcinoma (PDAC), borderline resectable at diagnosis
- Eastern Cooperative Oncology Group (ECOG) performance status 0-2
- Undergoing neoadjuvant chemotherapy with treatment plan including chemoradiation therapy and surgical resection
- Ability to read and speak English
Exclusion criteria
- Regular engagement in RT (2x/week targeting all major muscle groups)
- Screen failure for exercise safety based on PAR-Q
- Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease
- Recent fracture or acute musculoskeletal injury that precludes ability to participate in RT
- Numeric pain rating scale greater than or equal to a 7 out of 10
- Myopathic or rheumatologic disease that impacts physical function
Where
- Tampa, Florida
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced May 6, 2026 · Source of record for eligibility and locations