NCT07543861 · University of Michigan
A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease
(FOGSTAND)
What this study is about
This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease. 12 4-hour sessions will be performed to test the primary hypothesis that dynamic standing improves gait function compared to static standing and control sitting. This study has 2 phases.
View original scientific description
This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease. 12 4-hour sessions will be performed to test the primary hypothesis that dynamic standing improves gait function compared to static standing and control sitting. This study has 2 phases. Phase 1 will be an open-label study and Phase 2 will be an in-lab randomized controlled trial pilot study. This is phase 1 of the study.
Interventions
DEVICE
Dynamic Standing Desk
Participants will stand at the desk for 4 hours per session. During each session, the desk will move to prompt the participant to take small steps. Participants will take breaks as needed. Each participant will complete up to 12 sessions in the span of 6 weeks.
Primary outcome measures
Gait Speed
Time frame: Baseline and post-intervention (up to 6 weeks).
Gait speed will be measured during an 8.5-meter forward walking task measured in meters per second.
Movement Disorder Society-Unified Parkinson's Disease Rating Scale Part III
Time frame: Baseline and post-intervention (up to 6 weeks).
Clinical assessment that measures motor symptoms in Parkinson's Disease. Higher scores indicates more severe symptoms. Scores range from 0-132.
Montreal Cognitive Assessment
Time frame: Baseline and post-intervention (up to 6 weeks).
Clinical assessment that measures cognition. Higher scores indicate better cognition. Scores range from 0-30.
Timed Up and Go
Time frame: Baseline and post-intervention (up to 6 weeks).
Clinical assessment that measures the time it takes for a participant to stand from a chair, walk 3 meters, turn around, walk back to the chair and sit back down. Higher time indicates increased motor impairment.
5 Times Sit to Stand
Time frame: Baseline and post-intervention (up to 6 weeks).
Clinical assessment that measures the time it takes for a participant to sit and stand five times. Higher time indicates increased motor impairment.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Diagnosis of Parkinson's Disease
Exclusion criteria
- Inability to stand or walk without an assistive device
- History of symptoms in stance that preclude safe and comfortable participation, such as dizziness and lightheadedness, orthostasis, severe symptomatic leg or back musculoskeletal pain, or medication side effects
- Any other history of medical or psychiatric comorbidity, precluding safe participation in the project.
- History of symptomatic cardiovascular or pulmonary disease
- History of active rheumatic arthritis
- History of stroke or other neurologic conditions with significant residual sensorimotor deficits
- History of disabling chronic pain syndrome requiring narcotic analgesics
- Evidence of dementia (Mini Mental State Exam (or Montreal Cognitive Assessment test) \<24 and significant impairment in activities of daily living)
- Venous ulcerative stasis or severe varicosities.
- Pregnancy as determined by urine pregnancy test prior to DXA procedure in women of childbearing potential.
Where
- Ann Arbor, Michigan
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Apr 22, 2026 · Source of record for eligibility and locations