Loma Linda, CANCT04373317Now EnrollingIRB Ready

Parkinson's Disease Clinical Trial in Loma Linda, CA

Access cutting-edge parkinson's disease treatment through this phase 4 clinical trial at a research site in Loma Linda. Study-provided care at no cost to qualified participants.

Sponsored by VA Office of Research and Development

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Expert Care in Loma Linda

Access parkinson's disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related parkinson's disease treatment provided free

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Check if you qualify for this parkinson's disease clinical trial in Loma Linda, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Loma Linda

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Loma Linda site if eligible
  4. 4Begin participation

About This Parkinson's Disease Study in Loma Linda

Patients with Parkinson's disease (PD) sometimes experience symptoms affecting their movement, such as slowness, tremor, stiffness, and balance or walking problems. Many patients also have other symptoms not related to movement, called non-motor symptoms, which may affect one's mood or emotions, memory or thinking, or cause one to see or hear things that aren't real (hallucinations) or believe things that aren't true (delusions). Hallucinations or delusions, together called psychosis, occur in u

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

Diagnosis of Parkinson's Disease consistent with UK Parkinson's Disease Society Brain Bank Clinical Diagnostic Criteria
Psychosis \[with Neuropsychiatric Inventory (NPI) hallucinations (B) or delusions (A) score 4 or greater\]
Stable dose of PD medications for at least 2 weeks
If on an acetylcholinesterase inhibitor (AChEI) initially prescribed at least 3 months prior and stable dose (no dose or medication change) for past month
Informed other must provide informed consent and agree to attend all study visits. The informed other must be at least 18 years of age and have regular contact with the patient (on average at least 4 days per week and at least 2 hours per day, or at least 3 days per week and at least 4 hours per day, that is with patient) via in-person, video, or telephone
English-speaking INFORMED OTHER
Age 18 years or older
Must have regular contact with the patient (on average at least 4 days per week, and at least 2 hours per day, or at least 3 days per week and at least 4 hours pr day, that is with patient) via in-person, video, or telephone
Agree to attend all study visits
Be able to provide informed consent
English-speaking

Exclusion Criteria

Psychosis symptoms severe enough to preclude enrollment in a clinical trial and require prompt clinical care instead
Treatment with quetiapine \>50 mg/day or pimavanserin in the past 3 months, or quetiapine 50 mg/day or another antipsychotic in the past week prior to study randomization
Deep brain stimulation (DBS) surgery within 3 months or has had stimulator adjustments in the previous 2 weeks
History of a psychotic disorder prior to PD, including bipolar disorder, schizophrenia, schizoaffective disorder, and major depressive disorder with psychotic features, if it is thought to be the cause of the current psychosis symptoms
Suspected atypical parkinsonian disorder or dementia with Lewy bodies (DLB)
Psychosis secondary to other toxic or metabolic disorder
History of long QT syndrome
Documented chart evidence indicating persistent hypoglycemia, hypokalemia, hypomagnesemia that would put patient at increased risk for QTc prolongation.
History of ventricular arrhythmias, except when treated with an implantable cardioverter defibrillator (ICD) or pacemaker, or untreated or unstable atrial fibrillation/flutter
Currently taking medications that are moderate or strong CYP3A4 inducers or strong CYP3A4 inhibitors
Concomitant use of drugs that prolong the QTc interval with a known risk of Torsades de Pointes
Comorbid medical condition determined too severe by Site Investigator to allow participation in clinical trial
Failure to tolerate quetiapine or pimavanserin previously
Severe cognitive impairment (MoCA score \<5)
Nursing home placement at screening or planned placement during the study, unless approved by study Co-Chairs. Approval will depend upon nursing facility agreement to receive, return, and administer medications or allow participant to self-administer study medications; appropriate IO availability; and transportation availability for study visits.
Currently enrolled in another therapeutic or interventional study
Pregnant, or a female of child-bearing potential who is unwilling to use a reliable form of contraception

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Loma Linda?

Yes, this clinical trial (NCT04373317) has an active research site in Loma Linda, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Parkinson's Disease Treatment Options in Loma Linda, CA

If you're searching for parkinson's disease treatment options in Loma Linda, CA, this clinical trial (NCT04373317) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Loma Linda research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced parkinson's disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all parkinson's disease clinical trials near you to find additional studies recruiting in your area.

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