San Francisco, CANCT07625150Now EnrollingIRB Ready

Patellofemoral Osteoarthritis Clinical Trial in San Francisco, CA

Access cutting-edge patellofemoral osteoarthritis treatment through this clinical trial at a research site in San Francisco. Study-provided care at no cost to qualified participants.

Sponsored by University of California, San Francisco

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Expert Care in San Francisco

Access patellofemoral osteoarthritis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related patellofemoral osteoarthritis treatment provided free

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Check if you qualify for this patellofemoral osteoarthritis clinical trial in San Francisco, CA

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Why Participate?

  • No-Cost Study Care

  • Local to San Francisco

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit San Francisco site if eligible
  4. 4Begin participation

About This Patellofemoral Osteoarthritis Study in San Francisco

This project aims to develop an \[18F\] fluorodeoxyglucose (FDG) positron emission tomography (PET) / magnetic resonance imaging (MRI) method to locate the painful inflammation in PFJ OA associated with joint loading. \[18F\] FDG PET/MRI is an emerging pain imaging approach with enhanced sensitivity to painful hypermetabolic inflammation through evaluation of intracellular glucose utilization rate via (\[18F\]FDG PET) and fine anatomy details (MRI). The investigative group has shown its promise in revealing previously unidentified or unspecified pain generators in various musculoskeletal pain conditions. The investigators have also demonstrated the feasibility of visualizing the structural changes between unloaded and loaded knee joints with MRI, which can be easily adopted in the current PET/MRI setting. The main challenge in the proposed \[18F\]FDG PET/MRI approach is to differentiate the normal uptake of FDG for metabolic changes by weight-bearing from abnormal changes indicating eventual pain aggravation by weight-bearing and knee-flexion. The investigators have garnered the following two aims to validate the proposed method by comparing unloaded and loaded knee imaging results between PFJ OA pain patients and asymptomatic, matched controls.

Sponsor: University of California, San Francisco

Who Can Participate

Inclusion Criteria

Adult with the capacity to give informed consent
Ability to perform 25 single-leg squats
No traumatic knee injuries/surgeries since last visit for the parent study (IRB #21-34763)
No investigational drugs since last visit for the parent study (IRB #21-34763)
No contraindications to MRI or PET tracer since last visit for the parent study (IRB #21-34763)
Not taking steroid injections
Not pregnant
Additional inclusion criteria for healthy volunteers: Minimal pain (VAS=0-1) during a series of 25 single-leg squats on one or both legs

Exclusion Criteria

Inability to consent for themselves
Inability to perform 25 single-leg squats with the study leg
New traumatic knee injuries/surgeries since last visit for the parent study (IRB #21-34763)
Taking investigational drugs since last visit for the parent study (IRB #21-34763)
New contraindications to MRI or PET tracer since last visit for the parent study (IRB #21-34763)
Taking steroid injections
Additional exclusion criteria for healthy volunteers: VAS of 2 or greater during a series of 25 single-leg squats on both legs

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in San Francisco?

Yes, this clinical trial (NCT07625150) has an active research site in San Francisco, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Patellofemoral Osteoarthritis Treatment Options in San Francisco, CA

If you're searching for patellofemoral osteoarthritis treatment options in San Francisco, CA, this clinical trial (NCT07625150) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our San Francisco research site is actively enrolling participants for this clinical trial. You'll receive care from experienced patellofemoral osteoarthritis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all patellofemoral osteoarthritis clinical trials near you to find additional studies recruiting in your area.

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