Boston, MANCT06611501Now EnrollingIRB Ready

Pelvic Pain Clinical Trial in Boston, MA

Access cutting-edge pelvic pain treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Boston Children's Hospital

Quick Self-Assessment

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Expert Care in Boston

Access pelvic pain specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related pelvic pain treatment provided free

Apply for This Boston Location

Check if you qualify for this pelvic pain clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Pelvic Pain Study in Boston

The goal of this pilot trial is to learn if a novel non-hormonal treatment, metformin hydrochloride, works to treat pelvic pain in young women with endometriosis. The main questions it aims to answer are: * Is metformin superior to placebo in alleviating pain symptoms in young women with endometriosis? * Does metformin alter systemic inflammatory markers over 6 months in young women with endometriosis? Researchers will compare metformin to a placebo (a look-alike substance that contains no drug) to see if metformin works to treat pelvic pain. Participants will: * Take drug metformin or a placebo every day for 6 months * Visit the clinic three times: once at baseline (pre-treatment), once at 3 months, and once at 6 months * Keep a daily symptom diary to track pain, bleeding, and usage of any pain medications

Sponsor: Boston Children's Hospital

Who Can Participate

Inclusion Criteria

Female with surgically confirmed endometriosis, determined at laparoscopy
Current use for at least 2 months duration of a consistent hormonal therapy for endometriosis (either combination hormonal contraceptives or progestin-only therapy)
Current pelvic pain (score ≥ 3 on Visual Analog Scale) that has been present for at least 2 months prior to enrollment
Age 15 years to 35 years and premenopausal
Willingness to comply with visit schedule and protocol

Exclusion Criteria

Pre-menarche or post-menopause
Diagnosis of Type 1 or Type 2 Diabetes Mellitus
Severe renal dysfunction (creatinine \>1.4 mg/dL or eGFR below 45 mL/minute/1.73 m2
History of lactic acidosis or diabetic ketoacidosis
ALT or AST \> 2.5 times the upper limit of normal
Significant mental or chronic systemic illness that might confound pain assessment or the inability to complete the study
Current/planning pregnancy or breastfeeding
Inability to read English

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT06611501) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Pelvic Pain Treatment Options in Boston, MA

If you're searching for pelvic pain treatment options in Boston, MA, this clinical trial (NCT06611501) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced pelvic pain specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all pelvic pain clinical trials near you to find additional studies recruiting in your area.

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