Lubbock, TXNCT06303128Now EnrollingIRB Ready

Penicillin Allergy Clinical Trial in Lubbock, TX

Access cutting-edge penicillin allergy treatment through this clinical trial at a research site in Lubbock. Study-provided care at no cost to qualified participants.

Sponsored by James Tarbox, MD

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Expert Care in Lubbock

Access penicillin allergy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related penicillin allergy treatment provided free

Apply for This Lubbock Location

Check if you qualify for this penicillin allergy clinical trial in Lubbock, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Lubbock

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Lubbock site if eligible
  4. 4Begin participation

About This Penicillin Allergy Study in Lubbock

The goal of this clinical trial is to learn about dosing when testing to see if a penicillin allergy label can be removed from adults that had been labeled as "penicillin-allergic" previously. The main question it aims to answer is: \- In penicillin-allergic patients that are at low risk of having an allergic reaction, is a one-dose oral challenge with amoxicillin (a penicillin-based antibiotic) as safe and effective as a two-dose oral challenge? Participants will, after being identified as having a low-risk penicillin allergy, be administered oral amoxicillin in a controlled setting and then monitored for an allergic reaction. Researchers will compare participants that took one dose of amoxicillin to participants that took two doses of amoxicillin (a small dose and then a larger dose) to see if either group was more likely to develop an allergic reaction.

Sponsor: James Tarbox, MD

Who Can Participate

Inclusion Criteria

Expresses interest in participating by calling or filling out information form on study website
Reports an allergy to one of the following medications: penicillin VK, penicillin G, amoxicillin, ampicillin, dicloxacillin, flucloxacillin, nafcillin, oxacillin, amoxicillin- clavulanate, ampicillin-sulbactam. Subjects with an unspecified penicillin allergy are also eligible to participate.

Exclusion Criteria

Penicillin allergy deemed to be more than "low-risk" per PEN-FAST (score ≥ 3 points)
History of acute kidney injury (acute interstitial nephritis), severe liver impairment (drug- induced liver injury), serum sickness, or isolated drug fever attributed to a penicillin- based antibiotic
Anaphylaxis for any reason in the last year
Cognitive impairment where a collateral history could not be obtained and/or patient does not have capacity to consent for themselves
Pregnant (self-reported)
Any illness or condition that would increase the risk of participation in the study, per the evaluating clinician's judgment
Active treatment of or history of acute angle closure glaucoma
On H1- or H2-blockers (i.e. diphenhydramine, hydroxyzine, chlorpheniramine, cetirizine, levocetirizine, loratadine, fexofenadine or famotidine, ranitidine, cimetidine, nizatidine, respectively) within 72 hours of initiating direct oral challenge (will be counseled to discontinue prior to testing)
Actively receiving greater than stress dose steroid (hydrocortisone \>50mg four times a day or steroid equivalent)
Actively receiving any antibiotic
Relative contraindication: Patients on beta blockers and angiotensin converting enzyme inhibitors (ACE inhibitors) will have an open dialog with the study team regarding the risks and benefits of testing a low-risk penicillin allergy patient. A joint decision will be made based on the patient's preference and the physician's comfort level.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Lubbock?

Yes, this clinical trial (NCT06303128) has an active research site in Lubbock, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Penicillin Allergy Treatment Options in Lubbock, TX

If you're searching for penicillin allergy treatment options in Lubbock, TX, this clinical trial (NCT06303128) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Lubbock research site is actively enrolling participants for this clinical trial. You'll receive care from experienced penicillin allergy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all penicillin allergy clinical trials near you to find additional studies recruiting in your area.

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