Chestnut Hill, MANCT07225348Now EnrollingIRB Ready

Perioral Wrinkles Clinical Trial in Chestnut Hill, MA

Access cutting-edge perioral wrinkles treatment through this phase 4 clinical trial at a research site in Chestnut Hill. Study-provided care at no cost to qualified participants.

Sponsored by Skincare Physicians of Chestnut Hill

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Expert Care in Chestnut Hill

Access perioral wrinkles specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related perioral wrinkles treatment provided free

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Check if you qualify for this perioral wrinkles clinical trial in Chestnut Hill, MA

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Why Participate?

  • No-Cost Study Care

  • Local to Chestnut Hill

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chestnut Hill site if eligible
  4. 4Begin participation

About This Perioral Wrinkles Study in Chestnut Hill

The first goal of this clinical trial is to learn if topical application of PLLA in conjunction with a microneedling treatment works to treat perioral wrinkles in adults. The second goal is to see whether the application of topical PLLA is more effective before or after a microneedling treatment. The main questions it aims to answer are: * Is PLLA present within the MN channels from in vivo biopsy samples? * Is it safe to combine topical PLLA and MN in the treatment of perioral wrinkles, as determined by the incidence and severity of adverse events in healthy subjects? * Does overall aesthetic and skin texture improve in combining microneedling with topical PLLA in the treatment of mild to moderate perioral wrinkles? * Is it the treatment of topical PLLA more effective when applied before or after a microneedling treatment. Researchers will compare the application of PLLA before a microneedling treatment to a microneedling treatment with PLLA application after to see which treatment method is more effective. Participants will: \- receive 2 treatments spaced 4-6 weeks apart of topical PLLA and microneedling

Sponsor: Skincare Physicians of Chestnut Hill

Who Can Participate

Inclusion Criteria

Males and non-pregnant, non-lactating females 40-70 years of age
Fitzpatrick Skin Type I-IV
Wrinkle severity graded by the investigator (1-3 on Lemperle scale)
Able to provide written informed consent, understand and be willing to comply with all study related procedures and follow-up visits
Signed informed consent obtained before any study-specific procedure is performed.

Exclusion Criteria

Lesions suspicious for any malignancy, actinic keratosis, melasma, vitiligo, cutaneous papules/nodules or active inflammatory lesions in the area to be treated
Tenderness in the treatment rea
History of keloid formation or hypertrophic scarring
History of trauma or surgery to the treatment area
Scar present in the areas to be treated
Silicone or synthetic material injections in the areas to be treated
Injection of fat, collagen, hyaluronic acid or other dermal fillers in the areas to be treated within the previous 12 months
History of treatment with dermabrasion or laser in the areas to be treated within the previous 12 months
History of treatment with botulinum toxin injections in the areas to be treated within the prior 6 months
Active smokers (0.5 pack/day) or having quit within 3 months prior treatment
Active, chronic, or recurrent infection
History of compromised immune system or currently being treated with immunosuppressive agents
History of sensitivity to analgesic agents, Aquaphor, topical or local anesthetics
Excessive sun exposure and use of tanning beds or tanning creams within 30 days prior to treatment
Treatment with fish oil within 14 days prior to treatment
Treatment with aspirin or other blood thinning agents within 14 days prior to treatment
History or presence of any clinically significant bleeding disorder
Co-morbid condition that in the Investigator's opinion could limit ability to participate in the study or to comply with follow-up requirements
History of drug and/or alcohol abuse
Any issue that, at the discretion of the investigator, would interfere with assessment of safety or efficacy or compromise the subject's ability to safely undergo study procedures or give informed consent
Treatment with an investigational device or agent within 30 days before treatment or during the study period

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chestnut Hill?

Yes, this clinical trial (NCT07225348) has an active research site in Chestnut Hill, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Perioral Wrinkles Treatment Options in Chestnut Hill, MA

If you're searching for perioral wrinkles treatment options in Chestnut Hill, MA, this clinical trial (NCT07225348) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chestnut Hill research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced perioral wrinkles specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all perioral wrinkles clinical trials near you to find additional studies recruiting in your area.

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