Chicago, ILNCT06919081Now EnrollingIRB Ready

Persistent Corneal Epithelial Defect Clinical Trial in Chicago, IL

Access cutting-edge persistent corneal epithelial defect treatment through this clinical trial at a research site in Chicago. Study-provided care at no cost to qualified participants.

Sponsored by University of Illinois at Chicago

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Expert Care in Chicago

Access persistent corneal epithelial defect specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related persistent corneal epithelial defect treatment provided free

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Check if you qualify for this persistent corneal epithelial defect clinical trial in Chicago, IL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Chicago

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chicago site if eligible
  4. 4Begin participation

About This Persistent Corneal Epithelial Defect Study in Chicago

In this phase II randomized double-masked clinical trials, subjects with non-resolving corneal epithelial disease/defect (i.e., refractory to standard treatments for at least two weeks) will receive 8 weeks treatment of topical mesenchymal stem cell secretome or vehicle, with continued follow-up for up to Day 70.

Sponsor: University of Illinois at Chicago

Who Can Participate

Inclusion Criteria

Age · Patients 18 years of age or older
Ocular Health
Chronic corneal epithelial disease with fluorescein staining score 6 by NEI grading scale or persistent corneal epithelial defect present for longer than 14 days despite standard treatment
No objective clinical evidence of significant (\> 50%) improvement/worsening of the epithelial disease in the last 14 days
Epithelial disease refractory to conventional non-surgical treatments (e.g., preservative-free artificial tears, gels or ointments; discontinuation of preserved topical drops; anti-inflammatory therapy)
If both eyes of subject meet the inclusion criteria, the eye with the higher fluorescein staining score will be enrolled to the study.
Study Procedures
Only patients who satisfy all Informed Consent requirements may be included in the study. The patient and/or his/her legal representative must read, sign and date the Informed Consent document before any study-related procedures are performed. The Informed Consent form signed by patients and/or legal representative must have been approved by the UIC IRB for the current study. Patients must have the ability and willingness to comply with study procedures.

Exclusion Criteria

Ocular Health
Any active or suspected ocular infection (bacterial, viral, fungal or protozoal).
History of any ocular surgery (including laser or refractive surgical procedures) in the study eye within the 3 months prior to study enrollment.
Treatment with Oxervate in the study eye within 12 months of enrollment.
Study Procedures
Known hypersensitivity to one of the components of the study or procedural medications (e.g., fluorescein).
Use of any investigational agent within 4 weeks of screening visit.
Participation in another clinical study at the same time as the present study.
Participants who are pregnant at the time of study enrollment.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chicago?

Yes, this clinical trial (NCT06919081) has an active research site in Chicago, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Persistent Corneal Epithelial Defect Treatment Options in Chicago, IL

If you're searching for persistent corneal epithelial defect treatment options in Chicago, IL, this clinical trial (NCT06919081) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chicago research site is actively enrolling participants for this clinical trial. You'll receive care from experienced persistent corneal epithelial defect specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all persistent corneal epithelial defect clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Chicago, IL