La Jolla, CANCT05885412Now EnrollingIRB Ready

PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM) Clinical Trial in La Jolla, CA

Access cutting-edge pkp2 arrhythmogenic cardiomyopathy (pkp2-acm) treatment through this clinical trial at a research site in La Jolla. Study-provided care at no cost to qualified participants.

Sponsored by Rocket Pharmaceuticals Inc.

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Expert Care in La Jolla

Access pkp2 arrhythmogenic cardiomyopathy (pkp2-acm) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related pkp2 arrhythmogenic cardiomyopathy (pkp2-acm) treatment provided free

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Check if you qualify for this pkp2 arrhythmogenic cardiomyopathy (pkp2-acm) clinical trial in La Jolla, CA

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Why Participate?

  • No-Cost Study Care

  • Local to La Jolla

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit La Jolla site if eligible
  4. 4Begin participation

About This PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM) Study in La Jolla

This Phase 1 dose escalation trial will assess the safety and preliminary efficacy of a single dose intravenous infusion of RP-A601 in high-risk adult patients with PKP2-ACM.

Sponsor: Rocket Pharmaceuticals Inc.

Who Can Participate

Inclusion Criteria

Male or female ≥18 years at the time of signing the informed consent
Capable and willing to provide signed informed consent
Clinical diagnosis of ACM as defined by the 2010 revised Task Force Criteria (TFC)
Documentation of a pathogenic or likely pathogenic truncating variant in PKP2
History of Implantable Cardioverter-Defibrillator (ICD) implantation ≥6 months prior to enrollment
PVC frequency ≥500 per 24 hours by ambulatory rhythm monitoring
Left ventricular ejection fraction by echocardiogram or CMR ≥50% Key

Exclusion Criteria

Anti-AAVrh.74 capsid neutralizing antibody titer of \>1:40
Cardiomyopathy related to a genetic etiology other than PKP2 truncating variant
Previous participation in a study of gene transfer or gene editing
Severe Right Ventricular (RV) dysfunction
New York Heart Association (NYHA) Class IV heart failure.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in La Jolla?

Yes, this clinical trial (NCT05885412) has an active research site in La Jolla, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM) Treatment Options in La Jolla, CA

If you're searching for pkp2 arrhythmogenic cardiomyopathy (pkp2-acm) treatment options in La Jolla, CA, this clinical trial (NCT05885412) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our La Jolla research site is actively enrolling participants for this clinical trial. You'll receive care from experienced pkp2 arrhythmogenic cardiomyopathy (pkp2-acm) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all pkp2 arrhythmogenic cardiomyopathy (pkp2-acm) clinical trials near you to find additional studies recruiting in your area.

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