Rochester, MNNCT07594535Now EnrollingIRB Ready

Polycythemia Clinical Trial in Rochester, MN

Access cutting-edge polycythemia treatment through this phase 4 clinical trial at a research site in Rochester. Study-provided care at no cost to qualified participants.

Sponsored by Mayo Clinic

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Expert Care in Rochester

Access polycythemia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related polycythemia treatment provided free

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Check if you qualify for this polycythemia clinical trial in Rochester, MN

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Why Participate?

  • No-Cost Study Care

  • Local to Rochester

    Convenient for MN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Rochester site if eligible
  4. 4Begin participation

About This Polycythemia Study in Rochester

The purpose of this study is to evaluate the effect of the (angiotensin-converting enzyme) ACE inhibitor lisinopril on hemoglobin, hematocrit, and erythropoietin levels in patients with secondary polycythemia due to high-oxygen-affinity hemoglobin variants, oxygen-sensing pathway mutations, or other unexplained and potentially irreversible forms of erythrocytosis. This study aims to determine whether ACE inhibition can effectively reduce excessive erythrocytosis by modulating erythropoietin production.

Sponsor: Mayo Clinic

Who Can Participate

Inclusion Criteria

Hemoglobin in Men: \>16.5 g/dL (10.3 mmol/L).
Hemoglobin in Women \>16.0 g/dL (10.0 mmol/L).
BMI 18-40 kg/m2.

Exclusion Criteria

Positive JAK2 gene linked to Polycythemia Vera.
Current smoker or previous heavy smoker (\>15 pack years) who quit less than 12 months prior to enrollment.
Resting SpO₂ ≤ 94% on room air.
Current or recent (within the past 6 months) use of testosterone or androgen supplementation.
Any confounding respiratory or renal disease, including diagnosed or suspected sleep apnea, or stage 3 and up of chronic kidney disease.
Any confounding hematologic disease that may alter hemoglobin level.
Currently treated with ACE inhibitors.
Currently treated with potassium-sparing diuretics.
Currently on SGLT2 or use within 4 weeks prior to screening.
Baseline systolic blood pressure ≤90 mmHg.
Baseline systolic blood pressure \>160 mmHg or diastolic blood pressure \>100 mmHg.
Occupational exposure associated with chronically elevated COHb (auto repair, etc.).
History of anaphylaxis or angioedema.
Pregnant or breastfeeding.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Rochester?

Yes, this clinical trial (NCT07594535) has an active research site in Rochester, MN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Polycythemia Treatment Options in Rochester, MN

If you're searching for polycythemia treatment options in Rochester, MN, this clinical trial (NCT07594535) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Rochester research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced polycythemia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all polycythemia clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Rochester, MN