Austin, TXNCT06002633Now EnrollingIRB Ready

Post-Traumatic Stress Disorder Clinical Trial in Austin, TX

Access cutting-edge post-traumatic stress disorder treatment through this clinical trial at a research site in Austin. Study-provided care at no cost to qualified participants.

Sponsored by University of Texas at Austin

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Expert Care in Austin

Access post-traumatic stress disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related post-traumatic stress disorder treatment provided free

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Check if you qualify for this post-traumatic stress disorder clinical trial in Austin, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Austin

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Austin site if eligible
  4. 4Begin participation

About This Post-Traumatic Stress Disorder Study in Austin

Individuals with posttraumatic stress disorder (PTSD) have greater prevalence of alcohol use disorders (AUDs), with this comorbidity associated with worse illness outcomes, yet there remains limited mechanistic understanding of how PTSD confers risk for AUD. Understanding risk factors that associate with and predict the development of AUDs in PTSD could inform interventions and prevention efforts to reduce the rate of this comorbidity and improve outcomes of both disorders. Identifying predictors of risk requires longitudinal studies in PTSD aimed at capturing the mechanisms leading to the emergence of AUDs. There is growing evidence PTSD is related to biased decision-making during approach-avoidance conflict. Alcohol is also suggested to alter approach-avoidance decision-making. AUDs and acute alcohol intoxication is associated with a bias to seek out reward despite the possibility of threat (e.g., contributing to relapse following alcohol cue exposure and risky behavior during intoxication respectively). Alcohol-induced changes in approach-avoidance decision-making have not been investigated in the context of PTSD, but emerging data support the investigators' hypothesis that an interaction between alcohol and approach-avoidance conflict in PTSD may occur and contribute to risk for alcohol misuse and development of alcohol problems. No current data, cross-sectional or longitudinal, have tested the role of alcohol-induced changes in approach-avoidance conflict as a mechanism of risk for AUD among individuals with PTSD. To address this gap, the investigators propose to leverage the group's expertise in placebo-controlled alcohol administration procedures, longitudinal modeling, functional neuroimaging, and computational neuroscience approaches to investigate the effects of acute alcohol on approach-avoidance decision-making and mediating changes in multivariate neurocircuitry patterns in limbic, striatal, and salience networks.

Sponsor: University of Texas at Austin

Who Can Participate

Inclusion Criteria

for all participants:
between 21 and 60 years of age
having consumed at least 4 (men) or 3 (women) drinks on at least two occasions over the last year
For all subjects

Exclusion Criteria

history of significant medical illness, particularly if possible changes in cerebral tissue
neurologic abnormality including significant head trauma (loss of consciousness of ≥5-min)
full Scale IQ \<85
contraindication to MRI scanning
positive pregnancy test
severe alcohol use disorder
current severe cannabis use disorder
any current substance use disorder (other than alcohol, cannabis, or nicotine)
scores \> 15 on the alcohol Use Disorders Identification Test (AUDIT; part of phone screen)
ever being in an abstinence-oriented treatment program for alcohol use
reporting wanting to quit drinking but not being able to
any medical, religious, or other reasons for not drinking alcohol
history of heart attack, heart trouble, high blood pressure, diabetes, or liver disease
an adverse reaction to alcoholic beverages
reporting never consuming 4 (men) or 3 (women) or more drinks on at least two occasions over the last year
unwillingness to have a friend or family member drive them home after the alcohol administration sessions
Additional exclusion criteria for participants in PTSD and IPV-exposed but no PTSD groups:
not taking medications for \>4 weeks (i.e. participants must be stable on meds)
acute suicidality with intent
Additional exclusion criteria for participants in IPV-exposure but no PTSD group: \- history of PTSD
Additional exclusion criteria for healthy comparison subjects also include:
any prior psychiatric hospitalizations
lifetime history of a neurodevelopmental disorder, affective disorder, psychotic disorder, suicide attempt, or eating disorder
greater than 1 month of lifetime psychotropic medication

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Austin?

Yes, this clinical trial (NCT06002633) has an active research site in Austin, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Post-Traumatic Stress Disorder Treatment Options in Austin, TX

If you're searching for post-traumatic stress disorder treatment options in Austin, TX, this clinical trial (NCT06002633) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Austin research site is actively enrolling participants for this clinical trial. You'll receive care from experienced post-traumatic stress disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all post-traumatic stress disorder clinical trials near you to find additional studies recruiting in your area.

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