Palo Alto, CANCT07139743Now EnrollingIRB Ready

Progressive Multiple Sclerosis Clinical Trial in Palo Alto, CA

Access cutting-edge progressive multiple sclerosis treatment through this phase 1 clinical trial at a research site in Palo Alto. Study-provided care at no cost to qualified participants.

Sponsored by Autolus Limited

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Expert Care in Palo Alto

Access progressive multiple sclerosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related progressive multiple sclerosis treatment provided free

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Check if you qualify for this progressive multiple sclerosis clinical trial in Palo Alto, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Palo Alto

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Palo Alto site if eligible
  4. 4Begin participation

About This Progressive Multiple Sclerosis Study in Palo Alto

The main purpose of this study is to evaluate if obe-cel is safe or causes any side effects in adults with refractory progressive MS. The study also plans to assess if obe-cel can show early signs of efficacy in MS. The trial includes only 1 group of participants (single-arm). The study population comprises participants with progressive forms of MS, not responsive to highly effective therapies. Upon confirmation of study eligibility, participants will receive chemotherapy (used here for lymphodepletion) over 1 to 3 days in preparation for receiving a single obe-cel infusion. Participants will be checked closely in the 28 days following obe-cel treatment. After this, participants will be monitored to evaluate safety and efficacy up to 24 months.

Sponsor: Autolus Limited

Who Can Participate

Inclusion Criteria

Willing and able to give written informed consent for participation in the study.
Ability and willingness to adhere to the protocol's Schedule of Activities and other requirements.
Participants must be 18 to 60 years of age inclusive at the time of signing the informed consent form.
A female participant is eligible to participate if she is not pregnant or breastfeeding.
Current diagnosis of PMS.
Must have been treated previously with 2 disease-modifying therapies.

Exclusion Criteria

Any medications prohibited by the protocol.
Highly active multiple sclerosis.
Diagnosis of another autoimmune central nervous system condition.
Active or uncontrolled fungal, bacterial, viral infection.
History of malignant neoplasms unless disease-free for at least 24 months.
History of heart, lung, kidney, liver transplant or hematopoietic stem cell transplant.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Palo Alto?

Yes, this clinical trial (NCT07139743) has an active research site in Palo Alto, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Progressive Multiple Sclerosis Treatment Options in Palo Alto, CA

If you're searching for progressive multiple sclerosis treatment options in Palo Alto, CA, this clinical trial (NCT07139743) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Palo Alto research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced progressive multiple sclerosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all progressive multiple sclerosis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Palo Alto, CA