Baltimore, MDNCT06616597Now EnrollingIRB Ready

Prostate Cancer (Adenocarcinoma) Clinical Trial in Baltimore, MD

Access cutting-edge prostate cancer (adenocarcinoma) treatment through this clinical trial at a research site in Baltimore. Study-provided care at no cost to qualified participants.

Sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Quick Self-Assessment

See if you qualify for this Baltimore location

Preparing your pre-screening questions…

Expert Care in Baltimore

Access prostate cancer (adenocarcinoma) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related prostate cancer (adenocarcinoma) treatment provided free

Apply for This Baltimore Location

Check if you qualify for this prostate cancer (adenocarcinoma) clinical trial in Baltimore, MD

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Baltimore

    Convenient for MD residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Baltimore site if eligible
  4. 4Begin participation

About This Prostate Cancer (Adenocarcinoma) Study in Baltimore

To determine if dexamethasone or dexamethasone plus metronidazole restore sensitivity to abiraterone for the treatment of metastatic prostate cancer.

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Who Can Participate

Inclusion Criteria

Males aged 18 years of age and above.
Prostate adenocarcinoma
Absolute PSA ≥ 2.0 ng/mL at screening.
PSA (+/- radiographic) progression after having been on abiraterone and prednisone for at least 12 weeks.
Must be maintained on a GnRH analogue or have undergone orchiectomy.
Participants must have a life expectancy ≥ 6 months
Ability to swallow study medication tablets
Willing to abstain from alcohol during and for 14 days after treatment with metronidazole
Willing and able to collect urine and stool samples per protocol

Exclusion Criteria

Active infection or other medical condition that would make dexamethasone use contraindicated
Any chronic medical condition requiring a higher systemic dose of corticosteroid
Pathological finding consistent with small cell carcinoma of the prostate
Has imminent or established spinal cord compression based on clinical findings and/or MRI.
Chronic liver disease with Child-Pugh class C cirrhosis (see calculator in protocol)
Bilirubin \>3x ULN or AST and ALT \>5x ULN
Congenital prolonged QTc syndrome or QTc \> 500 msec (non-paced rhythm)
History of pituitary or adrenal dysfunction
Uncontrolled diabetes (Hemoglobin A1c \> 10%) or increasing doses of insulin within the past 4 weeks due to poorly controlled glucoses.
Administration of an investigational therapeutic or invasive surgical procedure (not including surgical castration) within 30 days of Cycle 1 Day 1 or currently enrolled in an investigational drug study
Any other serious illness or medical condition that would, in the opinion of the investigator, make this protocol unreasonably hazardous, including, but not limited to:
Any uncontrolled major infection.
Crohn's disease or ulcerative colitis.
Known or suspected toxic megacolon and/or known small bowel ileus.
Known allergy to any of the compounds under investigation.
On antibacterial therapy within 30 days prior to administration of study treatment.
Any condition or situation which, in the opinion of the investigator, would put the subject at risk, or interfere with the subject's participation in this study.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Baltimore?

Yes, this clinical trial (NCT06616597) has an active research site in Baltimore, MD that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Prostate Cancer (Adenocarcinoma) Treatment Options in Baltimore, MD

If you're searching for prostate cancer (adenocarcinoma) treatment options in Baltimore, MD, this clinical trial (NCT06616597) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Baltimore research site is actively enrolling participants for this clinical trial. You'll receive care from experienced prostate cancer (adenocarcinoma) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all prostate cancer (adenocarcinoma) clinical trials near you to find additional studies recruiting in your area.

More Prostate Cancer Trials in Baltimore, MD

See all prostate cancer clinical trials recruiting in Baltimore — not just this study.

Browse Prostate Cancer Trials in Baltimore →

Browse More Trials by Condition

Prostate Cancer TrialsAlzheimers Disease TrialsAtopic Dermatitis TrialsAll Conditions →

Ready to Join in Baltimore?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Baltimore, MD