Is NCT06402357 recruiting in Gainesville, FL?

Yes, NCT06402357 is currently recruiting participants at its Gainesville, FL location. This prostate cancer clinical trial is actively enrolling qualified participants.

How do I join the prostate cancer clinical trial in Gainesville?

To join this clinical trial in Gainesville, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Gainesville clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Prostate Cancer Clinical Trial in Gainesville, FL

About This Prostate Cancer Study in Gainesville

This study will investigate the efficacy of focal high intensity focused ultrasound (HIFU) in patients with localized radiorecurrent prostate cancer. This study will also investigate the change in participant quality of life after HIFU therapy as compared to before HIFU therapy.

Sponsor: University of Florida

Who Can Participate

Inclusion Criteria

Patient has elected to undergo focal high intensity focused ultrasound therapy for radiorecurrent prostate cancer

Males who are ≥ 18 years of age

Eastern Cooperative Oncology Group Performance Status of 0-3

A history of prostate cancer treated with radiation therapy +/- hormone therapy

MRI or prostate-specific membrane antigen (PSMA) PET region of interest (ROI)

Biopsy proven clinically significant prostate cancer (GG2 or above) recurrence within or ipsilateral to the ROI lesion (within 6 months of the MRI/PET).

Contralateral grade group 1 (GG1) prostate cancer disease to the ROI

PSMA PET negative for metastatic disease (within 6 months of the biopsy)

Subjects must not have more than one active malignancy at the time of enrollment (Subjects with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen \[as determined by the treating physician and approved by the PI\] may be included).

Written informed consent obtained from the subject and the subject agrees to comply with all the study-related procedures.

Exclusion Criteria

Contraindication to high intensity focused ultrasound (latex allergy, absent rectum, prior rectal fistula or significant rectal surgery making insertion of transrectal probe non-feasible or dangerous.)

Hormone therapy within 6 months of the screening period (Hormone therapy includes oral (relugolix, abiraterone, enzalutamide, apalutamide, darolutamide, casodex) injections (firmagon, Lupron))

History of Inflammatory Bowel Disease actively treated in last 3 years

Evidence of ≥ cT3 recurrent disease on imaging

Bilateral clinically significant prostate cancer

Presence of brachytherapy seeds still implanted

Presence of fiduciary markers which directly impede the successful treatment of the lesion of concern, as decided upon by the surgeon upon review of imaging

Large Calcification on CT or transrectal ultrasound which, as per the review of the surgeon, limits or hinders a quality high intensity focused ultrasound to the region of interest

Urethral stricture disease that has been active over the last 6 months or required further treatment than clean intermittent catheterization

No prior radiation therapy for prostate cancer

Subjects without a ROI on MRI or PET

Metastatic disease or locally advanced disease (defined by pelvic lymph node involvement or T4 disease) on PSMA PET

History of any other disease, metabolic dysfunction, clinical examination finding, or clinical laboratory finding giving reasonable suspicion of a disease or condition that contraindicates the use of protocol therapy or that might affect the interpretation of the results of the study or that puts the subject at high risk for treatment complications, in the opinion of the treating physician.

Prisoners or subjects who are involuntarily incarcerated, or subjects who are compulsorily detained for treatment of either a psychiatric or physical illness.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Gainesville?

Yes, this clinical trial (NCT06402357) has an active research site in Gainesville, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Prostate Cancer Treatment Options in Gainesville, FL

If you're searching for prostate cancer treatment options in Gainesville, FL, this clinical trial (NCT06402357) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Gainesville research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced prostate cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all prostate cancer clinical trials near you to find additional studies recruiting in your area.

Prostate Cancer Clinical Trial in Gainesville, FL

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