Houston, TXNCT05454488Now EnrollingIRB Ready

Prostate Cancer Clinical Trial in Houston, TX

Access cutting-edge prostate cancer treatment through this clinical trial at a research site in Houston. Study-provided care at no cost to qualified participants.

Sponsored by M.D. Anderson Cancer Center

Quick Self-Assessment

See if you qualify for this Houston location

Preparing your pre-screening questions…

Expert Care in Houston

Access prostate cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related prostate cancer treatment provided free

Apply for This Houston Location

Check if you qualify for this prostate cancer clinical trial in Houston, TX

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Houston

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Houston site if eligible
  4. 4Begin participation

About This Prostate Cancer Study in Houston

To learn if using cryotherapy to treat only the part of the prostate known to contain cancer is effective in controlling prostate cancer

Sponsor: M.D. Anderson Cancer Center

Who Can Participate

Inclusion Criteria

English-speaking adult males
Life expectancy over 10 years as assessed by treating physician
Prior to enrollment, MRI fusion biopsy of MRI-visible lesion required (as detailed below, which includes systematic biopsy cores)
Single focus GG2 or GG3 (additional GG1 allowed up to 6mm, noting that a single focus of disease is defined as an area seen on MRI that may be biopsied multiple times using targeted biopsies and have systematic core biopsies directly adjacent to targeted cores; all of which being considered as from the same focus)
Histologically confirmed adenocarcinoma of prostate
Organ-confined prostate cancer, clinical stage ≤T2bN0M0
Visible tumor on MRI
No clear evidence or high suspicion of extraprostatic extension or seminal vesical invasion on MRI
Biopsy via transperineal or transrectal approach with at least 2 cores of MRI visible lesions that are PIRADS 2 or higher and 12 core systematic biopsy template (

Exclusion Criteria

of cores from systematic template that overlap with targeted cores allowed).
Additional performance of microultrasound guided biopsy is allowed though not required. Please note that every effort will be made to correlate microultrasound findings with MRI, in order to determine if positive results are from the same MRIvisible focus. This determination will be made by the surgeon performing the biopsy.
Note that GGG 1 disease at sites other than ablation zone are allowed provided these are 6mm or less in size. PSA ≤15 ng/mL, or PSAD \<0.15 if PSA \>15 ng/mL
Physician can fully visualize the prostate on transrectal ultrasound on entry biopsy
Lesion anatomically amenable to cryotherapy treatment based on treating physician's discretion
Willing and able to read, understand and sign the study specific informed consent document
Willing and agreeable to comply with study protocol requirements, including focal cryotherapy ablation and all follow up visit requirements
Patients must consent to investigative laboratory protocol (such as, but not limited to, 2021- 0560) Exclusion criteria:
Gleason grade group 4 or 5 disease
Medical history or concurrent disease, which in the opinion of the investigator, poses the patient at significant peri-operative risk of complication due to anesthesia or the procedure
Active urinary tract infection
Any previous treatment for prostate cancer, including radiation therapy, hormonal treatment, biologic therapy for prostate cancer, or chemotherapy
Prior TURP or other prostate outlet procedure such as HoLEP, greenlight, microwave ablation, aquablation, UroLift, or simple prostatectomy.
Previous rectal surgery (other than hemorrhoidectomy) or history of rectal disease
Inability to obtain prostate MRI (ex. due to claustrophobia, pacemaker, or prohibitive implants)
Unwilling to consent to laboratory investigative protocol (such as, but not limited to, 2021- 0560)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT05454488) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Prostate Cancer Treatment Options in Houston, TX

If you're searching for prostate cancer treatment options in Houston, TX, this clinical trial (NCT05454488) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced prostate cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all prostate cancer clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Houston, TX