Is NCT06392295 recruiting in Miami, FL?

Yes, NCT06392295 is currently recruiting participants at its Miami, FL location. This prostate cancer clinical trial is actively enrolling qualified participants.

How do I join the prostate cancer clinical trial in Miami?

To join this clinical trial in Miami, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Miami clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Prostate Cancer Clinical Trial in Miami, FL

About This Prostate Cancer Study in Miami

The purpose of this prostate cancer research study is to learn about: 1. Improving control of prostate cancer using radiation therapy, delivered to the para-aortic and pelvic lymph nodes, in addition to systemic androgen suppression therapy; 2. Preserving quality of life after radiation therapy; 3. Leveraging imaging results from prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) scans to evaluate and manage disease progression.

Sponsor: University of Miami

Who Can Participate

Inclusion Criteria

Histologically proven prostate adenocarcinoma

Male, ≥ 18 years old

Oligorecurrent disease limited to the sub-diaphragmatic region with or without pelvic lymph nodes

a. No more than a total of 5 lesions on PSMA PET/CT scan (each lesion defined as positive with standardized uptake value (SUV) \> liver uptake and CT scan correlate)

b. No disease outside of the pelvic and sub-diaphragmatic para-aortic lymph nodes

c. At least one lesion in the sub-diaphragmatic pelvic or para-aortic lymph nodes

d. Non-bulky nodal disease (ie, tumor \<5 cm)

Prior pelvic radiation with disease response

a. Definitive radiation therapy to the prostate with or without treatment of the pelvic lymph nodes and/or

b. Salvage or adjuvant radiation therapy to the prostate bed following prostatectomy with or without treatment of the pelvic lymph nodes

Hormone-sensitive prostate cancer

Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-2

Ability to understand the investigational nature, potential risks and benefits of the research study, and willingness to sign the written informed consent and HIPAA document(s)

Willingness to fill out quality of life and psychosocial forms

Willingness to participate in our institution's Prostate Cancer Database Protocol (ID# 20090767)

Exclusion Criteria

No pathological diagnosis of prostate adenocarcinoma

Patient has more than 5 sites of metastatic disease

Patient has history of bone and/or visceral metastasis

No evidence of disease in the para-aortic or pelvic lymph nodes

No staging with PSMA PET/CT scan

History of prior radiation therapy outside the pelvis for prostate cancer

Bulky nodal disease \>5 cm in tumor size

Androgen deprivation therapy (ADT) or chemotherapy in the three months prior to staging PSMA PET/CT scan (suggesting oligoprogressive disease, rather than true oligorecurrent disease) or at time of study enrollment

Suspicious radiologic evidence of disease in the prostate on staging PSMA PET/CT scan without confirmatory negative prostate biopsy

Implanted hardware which limits treatment planning or delivery (determined by treating physician)

Castration-resistant prostate cancer (history of rising PSA with serum testosterone level \<50 ng/dL)

Patients with ECOG performance status \> 2

History of inflammatory bowel disease

History of malignancy other than prostate cancer except for non-melanoma skin cancer

Patients unable to consent or are prisoners

Unwilling to fill out quality of life and psychosocial forms

Participants with impaired decision-making capacity

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Miami?

Yes, this clinical trial (NCT06392295) has an active research site in Miami, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Prostate Cancer Treatment Options in Miami, FL

If you're searching for prostate cancer treatment options in Miami, FL, this clinical trial (NCT06392295) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Miami research site is actively enrolling participants for this clinical trial. You'll receive care from experienced prostate cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all prostate cancer clinical trials near you to find additional studies recruiting in your area.

Prostate Cancer Clinical Trial in Miami, FL

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