Cleveland, OHNCT05270733Now EnrollingIRB Ready

Psoriasis Clinical Trial in Cleveland, OH

Access cutting-edge psoriasis treatment through this clinical trial at a research site in Cleveland. Study-provided care at no cost to qualified participants.

Sponsored by University Hospitals Cleveland Medical Center

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Expert Care in Cleveland

Access psoriasis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related psoriasis treatment provided free

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Check if you qualify for this psoriasis clinical trial in Cleveland, OH

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cleveland

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cleveland site if eligible
  4. 4Begin participation

About This Psoriasis Study in Cleveland

The investigators propose to improve the possibility of reaching skin resolution by identifying certain markers or gene patterns that may predict patient response to certain psoriasis drugs ahead of time, thus eliminating or reducing the trial-and-error approach often employed. The ability to rule out (or in) specific therapeutics based on predictive efficacy would lead to a more personalized approach for psoriasis treatment. To do this, the investigators will be asking participants to try two different already on the market FDA-approved psoriasis drugs for 8 weeks at a time. The investigators will be monitoring participants skin for improvements as well as taking blood and skin samples at least three times. Investigators may also ask to take stool samples and/or skin swabs.

Sponsor: University Hospitals Cleveland Medical Center

Who Can Participate

Inclusion Criteria

Diagnosed with plaque-type psoriasis defined by either:
A board-certified dermatologist, OR
Dermatology Nurse Practitioner, OR
Skin punch biopsy
Insurance that includes an anti-p40 biologic (ustekinumab/.Stelara) and at least one anti-p19 biologic (guselkumab/Tremfya or risankizumab/Skyrizi)
Must be naive to ustekinumab, guselkumab, and risankizumab.
Involvement of body surface area (BSA) of at least 10% at screening and baseline visit.
Able to give informed consent under IRB approval procedures

Exclusion Criteria

Pregnant, breastfeeding, or planning to get pregnant 8 weeks before, during, and 8 weeks after the study.
Inability to provide informed consent
Inability to secure ustekinumab and either gusekumab or risankizumab for use while on trial
Use of tanning booths for at least 4 weeks prior to baseline visit
Current or recent use of topical steroid, tar, phototherapy, Vitamin D, or retinoid therapy to target lesions for at least 2 weeks prior to baseline visit and for duration of trial
Current or recent use of systemic or biologic therapy for at least 8 weeks prior to baseline visit
Patients with psoriatic arthritis or other rheumatologic diseases (e.g., Crohn's disease).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cleveland?

Yes, this clinical trial (NCT05270733) has an active research site in Cleveland, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Psoriasis Treatment Options in Cleveland, OH

If you're searching for psoriasis treatment options in Cleveland, OH, this clinical trial (NCT05270733) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cleveland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced psoriasis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all psoriasis clinical trials near you to find additional studies recruiting in your area.

More Psoriasis Trials in Cleveland, OH

See all psoriasis clinical trials recruiting in Cleveland — not just this study.

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Secure · Expert Care · Cleveland, OH