Provo, UTNCT07463703Now EnrollingIRB Ready

PTSD - Post Traumatic Stress Disorder Clinical Trial in Provo, UT

Access cutting-edge ptsd - post traumatic stress disorder treatment through this clinical trial at a research site in Provo. Study-provided care at no cost to qualified participants.

Sponsored by Cognitive FX

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related ptsd - post traumatic stress disorder treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Provo

    Convenient for UT residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Provo site if eligible
  4. 4Begin participation

About This PTSD - Post Traumatic Stress Disorder Study in Provo

This study tests a new brain stimulation treatment for post-traumatic stress disorder (PTSD), a condition that affects millions after trauma, causing symptoms like flashbacks, avoidance, mood changes, and heightened alertness. The investigators will enroll 15 adults (ages 18-65) with PTSD. First, participants get a brain scan (fMRI) to map their unique brain connections between areas involved in fear and control-the right amygdala (fear center) and right dorsolateral prefrontal cortex (control area). Using this personalized map, the investigators will apply accelerated transcranial magnetic stimulation (TMS), a safe, non-invasive method using magnetic pulses to adjust brain activity. Treatment lasts 5 days (10 short sessions daily, totaling 90,000 pulses) targeting the identified spot to strengthen control over fear responses. The study checks if this approach is practical, safe (tracking side effects like headaches), and shows early signs of reducing PTSD symptoms (measured by questionnaires and interviews). Follow-up lasts 3 months, with repeat scans to see brain changes. This study will see if personalized, fast-paced TMS targeting the disrupted fear-control brain circuit in PTSD can be feasible and safe, and preliminarily reduce symptoms by improving brain connectivity, potentially offering a quicker alternative to standard treatments.

Sponsor: Cognitive FX

Who Can Participate

Inclusion Criteria

Participants must meet ALL of the following criteria:
Age 18-65 years (inclusive)
DSM-5 diagnosis of PTSD confirmed by Clinician-Administered PTSD Scale for DSM-5 (CAPS-5)
PCL-5 total score ≥33 (indicating at least moderate symptom severity)
PTSD symptom duration ≥3 months
If taking psychotropic medications, stable dose for ≥6 weeks prior to enrollment with no planned changes during study participation
Able to provide written informed consent
English-speaking (required for validated assessment measures)
Able to attend daily treatment sessions for 5 consecutive weekdays
Eligible for 1.5T MRI scanning (no contraindications)

Exclusion Criteria

Participants meeting ANY of the following criteria will be excluded: TMS Contraindications:
Conductive, ferromagnetic, or other magnetic-sensitive metals implanted in the head or within 30 cm of the TMS coil (excluding the mouth), including:
Cochlear implants
Deep brain stimulators
Vagus nerve stimulators
Aneurysm clips or coils
Stents in the neck or brain
Any implanted electronic devices
History of seizure disorder (excluding single childhood febrile seizure)
First-degree family member with epilepsy
History of significant head trauma with loss of consciousness \>10 minutes
History of stroke, brain tumor, or other neurological disorder
Neurosurgical procedures involving brain tissue MRI Contraindications:
Implanted medical devices incompatible with MRI
Claustrophobia preventing MRI scan completion
Body size preventing MRI scanner entry Psychiatric Exclusions:
Lifetime history of psychotic disorder (schizophrenia, schizoaffective disorder, delusional disorder)
Lifetime history of bipolar I disorder
Current (within past month) moderate or severe substance use disorder per DSM-5 criteria
Current active suicidal ideation with intent or plan (Columbia Suicide Severity Rating Scale score ≥4)
Psychiatric hospitalization within past 3 months Medical Exclusions:
Unstable medical condition that, in the investigator's judgment, would interfere with study participation or pose safety risk
Pregnancy or breastfeeding (females of childbearing potential must have negative urine pregnancy test at screening)
Prior TMS treatment within past 3 months
Current participation in another interventional research study
Initiation of psychotherapy specifically for PTSD within past 3 months (stable ongoing therapy is permitted)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Provo?

Yes, this clinical trial (NCT07463703) has an active research site in Provo, UT that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

PTSD - Post Traumatic Stress Disorder Treatment Options in Provo, UT

If you're searching for ptsd - post traumatic stress disorder treatment options in Provo, UT, this clinical trial (NCT07463703) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Provo research site is actively enrolling participants for this clinical trial. You'll receive care from experienced ptsd - post traumatic stress disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all ptsd - post traumatic stress disorder clinical trials near you to find additional studies recruiting in your area.

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