NCT07290335 · Emory University
Optimizing Strategies to Maximize Patient Recruitment Yield
(OSPREY)
What this study is about
This platform trial aims to evaluate the effectiveness of different messaging strategies within a MyChart messaging program for research recruitment. MyChart is a patient portal system within the Electronic Medical Record (EMR), and messages can be sent directly to patients about research opportunities.
View original scientific description
This platform trial aims to evaluate the effectiveness of different messaging strategies within a MyChart messaging program for research recruitment. MyChart is a patient portal system within the Electronic Medical Record (EMR), and messages can be sent directly to patients about research opportunities.
Interventions
BEHAVIORAL
Baseline (control) message
The MyChart study recruitment program will send a message based on the current template, which is a brief message with a neutral tone.
BEHAVIORAL
Positively-valenced message
The MyChart study recruitment program will send a message based on a template that contains positively-valenced language related to the value/importance of the study.
BEHAVIORAL
Payment-inclusive message
The MyChart study recruitment program will send a message based on a template that includes more detailed information about participant payment.
BEHAVIORAL
Positively-valenced, payment-inclusive message
The MyChart study recruitment program will send a message based on a template that includes both positively-valenced language and detailed information about participant payment.
Primary outcome measures
Rate of "interested" response to recruitment messages
Time frame: Month 12
The primary endpoint is the rate at which individuals respond that they are interested in participating in the study to which they are invited. The primary outcome is a binary variable of "interested" response.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- for primary studies that are recruiting participants:
- All studies using the MyChart recruitment service are eligible, including both clinical trials and observational studies.
Exclusion criteria
- Criterion for primary studies that are recruiting participants:
- Not using MyChart for recruitment.
- At least 500 messages sent, 125 for each arm Inclusion Criteria for patients:
- All patients receiving messages via MyChart will be included
- Potential eligibility for a study using MyChart requirement based on the planned query/criteria for that study. Exclusion Criteria for patients:
- Excluded from primary study that is recruiting participants.
Where
- Atlanta, Georgia
Collaborators
American Heart Association, Georgia Clinical & Translational Science Alliance, National Center for Advancing Translational Sciences (NCATS)
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Feb 25, 2026 · Source of record for eligibility and locations