Tampa, FLNCT07315360Now EnrollingIRB Ready

Renal Impairment Clinical Trial in Tampa, FL

Access cutting-edge renal impairment treatment through this clinical trial at a research site in Tampa. Study-provided care at no cost to qualified participants.

Sponsored by Pfizer

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Expert Care in Tampa

Access renal impairment specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related renal impairment treatment provided free

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Check if you qualify for this renal impairment clinical trial in Tampa, FL

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Why Participate?

  • No-Cost Study Care

  • Local to Tampa

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Tampa site if eligible
  4. 4Begin participation

About This Renal Impairment Study in Tampa

The purpose of this study is to learn how the study medicine PF-07328948 is processed by the body and how safe and tolerable it is in adults with different levels of kidney function. The study will include participants who: * Are aged 18 to 80 years. * Either have normal kidney function or long-term reduced kidney function (moderate or severe). * Have a BMI (body mass index) of 17.5 to 40 kilogram per meter squared, inclusive, and a total body weight of more than or equal to 45 kilograms or 99 pounds. All participants will receive a single dose of PF-07328948 as a tablet taken by mouth. Participants will stay at a clinical research unit for about 6 days to receive the study medicine and undergo safety checks. Total participation lasts up to 64 days, including screening, inpatient stay, and a follow-up call. The study is not randomized or blinded, meaning all participants and study staff know which treatment is being given. Group assignment is based on kidney function tests done during screening. The results will help researchers understand how reduced kidney function affects the way PF-07328948 works in the body.

Sponsor: Pfizer

Who Can Participate

Inclusion Criteria

Male or female of nonchildbearing potential, between the ages of 18 and 80 years, at the screening visit.
BMI of 17.5 to 40.0 kg/m2 (inclusive), and a total body weight ≥45 kg (99 lbs).
Stable renal function, defined as ≤25% difference between 2 measurements of eGFR.
Group 1 only: at screening, no clinically relevant abnormalities identified by a detailed medical history, physical exam, including blood pressure and pulse rate measurement, ECG and clinical laboratory tests.
Group 1 only: normal renal function (mean eGFR ≥90 mL/min) based on an average of measures from the screening visits.
Groups 2 \& 3 only: good general health considered acceptable with the expected health status of individuals with chronic renal impairment.
Groups 2 \& 3 only: chronic renal impairment, defined by the following mean eGFR criteria (based on screening visits):
Severe RI: 15 ≤ mean eGFR \<30 mL/min, not requiring hemodialysis.
Moderate RI: 30 ≤ mean eGFR \<60 mL/min.

Exclusion Criteria

Any condition possibly affecting drug absorption.
At screening, a positive result for HIV antibodies.
History of renal, liver, or heart transplantation.
Urinary incontinence without catheterization.
Evidence of a prothrombotic state, including history of deep vein thrombosis, pulmonary embolism, or arterial thrombosis, or known genetic predisposition.
Use of an investigational product within 30 days or 5 half-lives (whichever longer).
A positive urine drug test or breath alcohol test at screening or admission to study clinic.
Group 1 only: evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurological, or allergic disease.
Group 1 only: screening ECG demonstrating QTcF interval \>450 ms or a QRS interval \>120 ms.
Group 1 only: screening seated systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg
Group 2 \& 3 only: presence of acute renal disease
Group 2 \& 3 only: requiring dialysis or anticipated need for dialysis
Group 2 \& 3 only: listed for solid organ transplantation
Groups 2 \& 3 only: persistent severe, uncontrolled hypertension at screening, admission to study clinic, or pre-dose on Day 1.
Groups 2 \& 3 only: screening ECG demonstrating a QTcF interval \>470 ms or a QRS interval \>120 ms.
Groups 2 \& 3 only: unstable medical conditions or comorbidities that would interfere with study participation

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Tampa?

Yes, this clinical trial (NCT07315360) has an active research site in Tampa, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Renal Impairment Treatment Options in Tampa, FL

If you're searching for renal impairment treatment options in Tampa, FL, this clinical trial (NCT07315360) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Tampa research site is actively enrolling participants for this clinical trial. You'll receive care from experienced renal impairment specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all renal impairment clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Tampa, FL