Boston, MANCT06033703Now EnrollingIRB Ready

Rhegmatogenous Retinal Detachment Clinical Trial in Boston, MA

Access cutting-edge rhegmatogenous retinal detachment treatment through this phase 1/2 clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Massachusetts Eye and Ear Infirmary

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Expert Care in Boston

Access rhegmatogenous retinal detachment specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related rhegmatogenous retinal detachment treatment provided free

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Check if you qualify for this rhegmatogenous retinal detachment clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Rhegmatogenous Retinal Detachment Study in Boston

This study has two main objectives. The first objective is to study the pharmacokinetics of topical netarsudil administration in the posterior segment of the eye, where netarsudil must exert its effect in order to prevent formation of tractional membranes. The second objective is to assess the safety profile of topical netarsudil in the pre- and post-operative periods. A secondary objective of the study is to begin to assess signs of efficacy in preventing formation of tractional membranes post-operatively.

Sponsor: Massachusetts Eye and Ear Infirmary

Who Can Participate

Inclusion Criteria

Patients \> 18 years old
Patients presenting for primary rhegmatogenous retinal detachment repair within 28 days of symptom onset
Patients undergoing vitrectomy or vitrectomy with scleral buckle

Exclusion Criteria

Patient unable to give consent
Patient unable to follow-up
Prior history of retinal detachment incisional surgery in presenting eye
Prior history of open globe injury to presenting eye
Prior history of glaucoma surgery to presenting eye I.e., Status post trabeculectomy, Ahmed tube placement, minimally invasive glaucoma surgery, actively on glaucoma medication
Prior history of corneal disease, or history of corneal edema
Patient already on topical netarsudil in presenting eye
Patient without natural lens or intraocular lens implant (I.e., aphakic patients)
Patients with intraocular pressure \<8mm Hg in operative eye
Active or chronic or recurrent uncontrolled ocular or systemic disease
Active or history of chronic or recurrent inflammatory eye disease
Diagnosis of proliferative diabetic retinopathy
Signs of ocular infection at presentation in either eye
Known or suspected sensitivity or allergy to any of the medications used in the operation or postoperatively
Inability to use/ apply topical eye drops The proliferative vitreoretinopathy cohort will have the following selection criteria: Inclusion criteria:
Patients \> 18 years old
Patient presenting with retinal detachment due with proliferative vitreoretinopathy (grade C or higher) or retinal detachment associated with open globe trauma
Patients undergoing vitrectomy or vitrectomy with scleral buckle Exclusion criteria:
Patient unable to give consent
Patient unable to follow-up
Prior history of glaucoma surgery to presenting eye I.e., Status post trabeculectomy, Ahmed tube placement, minimally invasive glaucoma surgery
Patient already on topical netarsudil in presenting eye
Patients with intraocular pressure \<8mm Hg in operative eye
Active or chronic or recurrent uncontrolled ocular or systemic disease
Active or history of chronic or recurrent inflammatory eye disease
Diagnosis of severe nonproliferative or proliferative diabetic retinopathy or vasoproliferative disease in operative eye
Signs of ocular infection at presentation in either eye
Known or suspected sensitivity or allergy to any of the medications used in the operation or postoperatively
Inability to use/ apply topical eye drops
No Light Perception vision in operative eye
Failure to achieve intraoperative reattachment

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT06033703) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Rhegmatogenous Retinal Detachment Treatment Options in Boston, MA

If you're searching for rhegmatogenous retinal detachment treatment options in Boston, MA, this clinical trial (NCT06033703) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced rhegmatogenous retinal detachment specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all rhegmatogenous retinal detachment clinical trials near you to find additional studies recruiting in your area.

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